L. Rossi

Engineered Oxalate decarboxylase boosts activity and stability for biological applications

This study engineers Oxalate decarboxylase to improve its activity and stability for medical applications in hyperoxaluria treatment.

Structure of hepatitis B/D antiviral drug Bulevirtide bound to its receptor protein NTCP

The paper determines the cryo-EM structure of bulevirtide bound to NTCP, revealing its mechanism of inhibiting HBV/HDV entry and providing insights for drug development.

Genetic evidence of a hybrid swarm between Alpine ibex and domestic goat

The paper identifies ongoing hybridization between Alpine ibex and domestic goat using SNP analysis and phenotype data, revealing a hybrid swarm in specific regions.

Native extracellular matrix promotes human neuromuscular organoid morphogenesis and function.

This study shows that decellularized skeletal muscle ECM guides hiPSC differentiation into structured neuromuscular organoids with functional neuromuscular junctions and disease-mimicking contractility.

High-fructose feeding suppresses cold-stimulated brown adipose tissue glucose uptake in young men independently of changes in thermogenesis and the gut microbiome

This study shows high-fructose diets impair brown adipose tissue glucose uptake in young men without affecting thermogenesis, gut microbiome, or body mass.

Acidity and sulfur oxidation intermediate concentrations controlled by O2-driven partitioning of sulfur oxidizing bacteria in a mine tailings impoundment

The paper investigates sulfur oxidation by bacteria in a mine tailings impoundment, showing how oxygen drives niche partitioning among sulfur-oxidizing bacteria and affects acidity and thiosulfate levels.

Fetal gut colonization: meconium does not have a detectable microbiota before birth

This study investigates whether fetal meconium contains detectable microbiota before birth and finds no microbial signal distinct from controls, suggesting colonization occurs after birth.

Outwitting planarians antibacterial defence mechanisms: Rickettsiales bacterial trans-infection from Paramecium multimicronucleatum to planarians

The paper demonstrates that a Rickettsia-like endosymbiont from a ciliate can be trans-infected into planarians, detected up to day 7 post-infection.