Author

L. Sabbagh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1

Frequent Co-Authors

A. A. Sharma· 1 shared A. I. Basbaum· 1 shared A. Makriyannis· 1 shared A. Raad· 1 shared B. K. Shoichet· 1 shared B.-K. Hong· 1 shared C. Benne· 1 shared C. Iliopoulos-Tsoutsouvas· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. A. Sharma

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

B lymphocytes acquire myeloid and autoimmune phenotypes via the downregulation of lymphocyte-specific protein-1

N. Lee, B.-K. Hong, S. You, R. Kwon, J. Kwon, E. Choi, K.-G. Lee, Y.-M. Kim, Y. Li, J. Kim, Y.-J. Park, Y. Chung, S.-H. Im, L. Sabbagh, C.-S. Cho, W.-U. Kim

This study shows that LSP1 deficiency in B cells leads to myeloid-like traits and autoantibody production, accelerating lupus in mice and correlating with reduced LSP1 in lupus patients.

bioRxiv · Jun 28, 2024 · PreprintImmunology

Large library docking for cannabinoid-1 receptor agonists with reduced side effects

T. A. Tummino, C. Iliopoulos-Tsoutsouvas, J. M. Braz, E. S. O'Brien, R. M. Stein, V. Craik, N. K. Tran, S. Ganapathy, F. Liu, Y. Shiimura, F. Tong, T. C. Ho, D. S. Radchenko, Y. S. Moroz, S. R. Rosado, , B. K. Shoichet

The paper identifies a new cannabinoid-1 receptor agonist with reduced side effects through large library docking and experimental validation.

bioRxiv · Feb 27, 2023 · PreprintPharmacology & Toxicology

Infusion of CCR5 Gene-Edited T Cells Allows Immune Reconstitution, HIV Reservoir Decay, and Long-Term Virological Control

J. Zeidan, A. A. Sharma, G. Lee, A. Raad, R. Fromentin, S. Fourati, K. Ghneim, G. P. Sanchez, C. Benne, G. Canderan, F. A. Procopio, R. Balderas, G. Monette, J. P. Lalezari, J. M. Heffernan, , R.-P. Sekaly

This study shows that infusing CCR5 gene-edited T cells improves immune function, reduces HIV reservoirs, and enables long-term viral control without ART.

bioRxiv · Feb 28, 2021 · PreprintImmunology