Author

L. Starrs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

G. Burgio· 5 shared A. Mathur· 2 shared B. McMorran· 2 shared F.-J. Li· 2 shared S. Foote· 2 shared S. M. Man· 2 shared A. Ehmann· 1 shared C. B. Schnider· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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5 shared papersMicrobiology

G. Burgio

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

GBP1 promotes killing of multidrug-resistant Acinetobacter baumannii and promotes host protection via interferon signalling and inflammasome activation.

F.-J. Li, L. Starrs, A. Mathur, D. Enosi-Tuipolotu, S. M. Man, G. Burgio

This study shows GBP1 and interferon signaling enhance host defense against multidrug-resistant A. baumannii by promoting inflammasome activation and killing resistant bacteria.

bioRxiv · Oct 24, 2022 · PreprintMicrobiology

Differential activation of NLRP3 inflammasome by Acinetobacter baumannii strains

F.-J. Li, L. Starrs, A. Mathur, H. Ishii, S. M. Man, G. Burgio

This study compares the activation of the NLRP3 inflammasome and programmed cell death by different Acinetobacter baumannii strains in macrophages and mice, revealing strain-specific differences in virulence and immune response.

bioRxiv · Apr 29, 2022Microbiology

Exploring heteroaromatic rings as a replacement for the labile amide of antiplasmodial pantothenamides

J. Guan, C. Spry, E. Tjhin, P. Yang, T. Kittikool, V. Howieson, H. Ling, L. Starrs, G. Burgio, K. J. Saliba, K. Auclair

This study replaces the amide group in pantothenamides with heteroaromatic rings to improve antiplasmodial activity against Plasmodium species.

bioRxiv · Oct 2, 2020Pharmacology & Toxicology

Host porphobilinogen deaminase deficiency confers malaria resistance in Plasmodium chabaudi but not in Plasmodium falciparum or Plasmodium berghei during intraerythrocytic growth

C. B. Schnider, H. Yang, L. Starrs, A. Ehmann, F. Rahimi, E. Di Pierro, G. Graziadei, K. Matthews, T. de Koning-Ward, D. C. Bauer, S. Foote, G. Burgio, B. McMorran

This study identifies a host mutation in porphobilinogen deaminase (PBGD) that confers resistance to Plasmodium chabaudi but not other Plasmodium species during blood-stage infection.

bioRxiv · Jun 13, 2020Microbiology

KCC1 Activation protects Mice from the Development of Experimental Cerebral Malaria.

E. Hortle, L. Starrs, F. Brown, J. Stephen, D. Curtis, B. McMorran, S. Foote, G. Burgio

This study shows that KCC1 activation protects mice from experimental cerebral malaria by increasing CD4+ T cells and TNF- response.

bioRxiv · Jan 31, 2019Microbiology