Author

L. Swadling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Meyer· 1 shared C. Green· 1 shared D. Bailey· 1 shared E. Barnes· 1 shared G. Alsaleh· 1 shared H. Wang· 1 shared H. Zhang· 1 shared I. Panse· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPhysiology

A. Meyer

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2 papers

Recent·Most cited

An ACAT inhibitor regulates SARS-CoV-2 replication and antiviral T cell activity

N. M. Schmidt, P. A. Wing, R. Peters, R. Brown, H. Wang, L. Swadling, J. Newman, N. Thakur, K. Shionoya, S. B. Morgan, T. S. Hinks, K. Watashi, D. Bailey, S. B. Hansen, M. K. Maini, J. A. McKeating

This paper shows that ACAT inhibitors like Avasimibe reduce SARS-CoV-2 replication and enhance antiviral T cell activity in patients.

bioRxiv · Apr 12, 2022 · PreprintImmunology

Autophagy in T cells from aged donors is maintained by spermidine, and correlates with function and vaccine responses

G. Alsaleh, I. Panse, L. Swadling, H. Zhang, A. Meyer, J. Lord, E. Barnes, P. Klenerman, C. Green, K. Simon

This study shows that spermidine maintains autophagy in aged human T cells, improving vaccine responses by enhancing IFN-gamma secretion and T cell function.

bioRxiv · Jun 1, 2020Physiology