Author

L. T. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:plant (other)· 1

Frequent Co-Authors

A. J. R. Cooper· 2 shared A. M. Minassian· 2 shared C. A. Long· 2 shared C. M. Nielsen· 2 shared J. R. Barrett· 2 shared J. Tan· 2 shared K. McHugh· 2 shared K. Miura· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. J. R. Cooper

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Author profile →

3 papers

Recent·Most cited

Analysis of the Diverse Antigenic Landscape of the Malaria Invasion Protein RH5 Identifies a Potent Vaccine-Induced Human Public Antibody Clonotype

J. R. Barrett, D. Pipini, N. D. Wright, A. J. R. Cooper, G. Gorini, D. Quinkert, A. M. Lias, H. Davies, C. Rigby, M. Aleshnick, B. G. Williams, W. J. Bradshaw, N. G. Paterson, T. Martinson, P. Kirtley, , S. J. Draper

The paper characterizes human antibodies against PfRH5, identifies key features of potent inhibitors, and demonstrates their prophylactic potential against malaria.

Cell · Sep 1, 2024Peer-reviewedImmunology

Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5

L. T. Wang, A. J. R. Cooper, B. Farrell, K. Miura, A. Diouf, N. Muller-Sienerth, C. Crosnier, L. Purser, M. Maciuszek, J. R. Barrett, K. McHugh, C. Tucker, S. Li, S. Doumbo, D. Doumtabe, , J. Tan

The paper identifies potent neutralizing antibodies against the malaria antigen RH5 from natural infection, showing they target similar epitopes as vaccine-induced antibodies.

bioRxiv · Oct 4, 2023Immunology

The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria

L. T. Wang, N. K. Hurlburt, A. Schon, B. J. Flynn, L. S. Pereira, M. Dillon, Y. Flores-Garcia, B. Bonilla, F. Zavala, A. H. Idris, J. R. Francica, M. Pancera, R. A. Seder

This study shows that the L9 antibody's light chain is essential for binding PfCSP minor repeats and enhancing neutralization of malaria sporozoites.

bioRxiv · Aug 11, 2021Immunology