Author

L. Van Den Bosch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Claeys· 1 shared A. Dashwood· 1 shared A. de Boer· 1 shared A. Gitler· 1 shared A. Kerstens· 1 shared A. Liston· 1 shared A. S. Holehouse· 1 shared B. Boeckx· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Claeys

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma

L. Finotto, B. Cole, W. Giese, E. Baumann, A. Claeys, M. Vanmechelen, B. Decraene, M. Derweduwe, N. Dubroja Lakic, G. Shankar, M. Nagathihalli Kantharaju, J. P. Albrecht, I. Geudens, F. Stanchi, K. L. Ligon, , H. Gerhardt

The paper identifies LGALS1 as an immunomodulating target in glioblastoma by analyzing GAM-GBM interactions using single-cell RNA sequencing and zebrafish models.

bioRxiv · Apr 27, 2023 · PreprintCancer Biology

Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation

L. Yshii, E. Pasciuto, P. Bielefeld, L. Mascali, P. Lemaitre, M. Marino, J. Dooley, L. Kouser, S. Verschoren, V. Lagou, H. Kemps, P. Gervois, A. de Boer, O. Burton, J. Wahis, , A. Liston

This study delivers IL2 to astrocytes in the brain to increase resident Tregs and protect against neuroinflammation without affecting the peripheral immune system.

bioRxiv · Feb 28, 2022Immunology

Spontaneous driving forces give rise to protein-RNA condensates with coexisting phases and complex material properties

S. Boeynaems, A. S. Holehouse, V. Weinhardt, D. Kovacs, J. Van Lindt, C. Larabell, L. Van Den Bosch, R. Das, P. Tompa, R. V. Pappu, A. Gitler

This study shows that spontaneous interactions between proteins and RNA can form multi-layered condensates with distinct material properties and specific amino acid and RNA sequence dependencies.

bioRxiv · Dec 11, 2018Biophysics