Author

A. Claeys

KU Leuven

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Research Focus:drug response / drug discovery· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:proteomics· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

B. Cole· 2 shared F. De Smet· 2 shared K. L. Ligon· 2 shared M. Derweduwe· 2 shared S. De Vleeschouwer· 2 shared A. Martinez· 1 shared A. Soldano· 1 shared Anggraeini Puspitasari-KokkoiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

B. Cole

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Heterogeneous and conserved radiation responses reveal FOXM1-dependent regulation of microcephaly genes in glioblastoma

Lou Van Eupen, Emre Etlioglu, Kevin Tabury, Keith Lloyd Ligon, Rosa Aguirre, Marleen Derweduwe, A. Claeys, Anggraeini Puspitasari-Kokko, Irina Primac, Frederik De Smet, Roel Quintens

The paper identifies FOXM1-dependent regulation of microcephaly genes in glioblastoma radiation response, showing that FOXM1 inhibition enhances radiosensitivity.

bioRxiv · Sep 2, 2026 · PreprintCancer Biology

Preclinical exploration of the DNA Damage Response pathway using the interactive neuroblastoma cell line explorer CLEAN.

J. Gabre, P. Merseburger, A. Claeys, J. Siaw, S.-L. Bekaert, F. Speleman, B. Hallberg, R. Palmer, J. Van den Eynden

The paper introduces CLEAN, a web tool for exploring neuroblastoma data, focusing on DNA damage response to identify drug targets.

bioRxiv · Sep 17, 2023Cancer Biology

Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma

L. Finotto, B. Cole, W. Giese, E. Baumann, A. Claeys, M. Vanmechelen, B. Decraene, M. Derweduwe, N. Dubroja Lakic, G. Shankar, M. Nagathihalli Kantharaju, J. P. Albrecht, I. Geudens, F. Stanchi, K. L. Ligon, , H. Gerhardt

The paper identifies LGALS1 as an immunomodulating target in glioblastoma by analyzing GAM-GBM interactions using single-cell RNA sequencing and zebrafish models.

bioRxiv · Apr 27, 2023 · PreprintCancer Biology

Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma

D. Panovska, P. Nazari, B. Cole, P.-J. Creemers, M. Derweduwe, L. Solie, S. Van Gassen, A. Claeys, T. Verbeke, Y. Saeys, D. Van Der Planken, F. M. Bosisio, E. Put, S. Bamps, P. Clement, , F. De Smet

The paper introduces PROSPERO, a single-cell assay to evaluate therapy response in glioblastoma by measuring molecular drug responses in fresh tumor samples, revealing limited therapeutic capacity and cellular plasticity.

bioRxiv · Oct 17, 2022 · PreprintCancer Biology

The Amyloid Precursor Protein is a conserved Wnt receptor

T. Liu, M. Nicolas, T. Zhang, H. Rice, A. Soldano, A. Claeys, I. Petrova, L. Fradkin, B. De Strooper, B. A. Hassan

This study identifies Wnt ligands as binding partners of APP, showing that Wnt3a stabilizes APP while Wnt5a targets it for degradation, with functional consequences for neuronal development.

bioRxiv · Jan 18, 2021Cell Biology