Author

Lana Harshman

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Nadav AhituviD· 2 shared Abbey BlakeiD· 1 shared Aki UshikiiD· 1 shared Alexandra M. StendahliD· 1 shared Amy Ly· 1 shared Ana C. LimaiD· 1 shared Archana Raja· 1 shared Candace S. Y. ChaniD· 1 shared

Activity by Year

2016-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersGenetics

Nadav AhituvORCID

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3 papers

Recent·Most cited

Deletion of an evolutionarily conserved TAD boundary compromises spermatogenesis in mice

Ana C. Lima, Mariam Okhovat, Alexandra M. Stendahl, Jake VanCampen, Kimberly A. Nevonen, Jarod Herrera, Weiyu Li, Lana Harshman, Ran Yang, Lev M. Fedorov, Katinka A. Vigh‐Conrad, Nadav Ahituv, Donald F. Conrad, Lucia Carbone

This study shows that deleting a conserved TAD boundary near Dmrtb1 and Lrp8 in mice impairs spermatogenesis but not fertility.

bioRxiv · Jul 8, 2024 · PreprintGenetics

Integrative single-cell characterization of hypothalamus sex-differential and obesity-associated genes and regulatory elements

Hai P. Nguyen, Candace S. Y. Chan, Dianne Laboy Cintrón, Rory R. Sheng, Lana Harshman, Mai Nobuhara, Aki Ushiki, Cassidy Biellak, Kelly An, Gracie Gordon, F. Mifsud, Abbey Blake, Eric Jinsheng Huang, Martin Hemberg, Christian Vaisse, Nadav Ahituv

The paper integrates single-cell RNA and ATAC-seq data from mouse and human hypothalamus to identify sex-specific genes and obesity-associated regulatory elements.

bioRxiv · Nov 6, 2022 · PreprintNeuroscience

High-Quality Assembly of an Individual of Yoruban Descent

Karyn Meltz Steinberg, Tina Graves Lindsay, Valerie A. Schneider, Mark J.P. Chaisson, Chad Tomlinson, John Huddleston, Patrick Minx, Milinn Kremitzki, Derek Albrecht, Vincent Magrini, Sean McGrath, Archana Raja, Carl Baker, Lana Harshman, LaDeana W. Hillier, , Richard K. Wilson

This paper presents a high-quality de novo assembly of a Yoruban individual using multiple sequencing technologies and demonstrates the utility of diploid assembly in improving genome quality.

bioRxiv · Aug 2, 2016 · PreprintBioinformatics