Author

Kelly An

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:ChIP-seq· 1

Frequent Co-Authors

Nadav AhituviD· 5 shared Aki UshikiiD· 2 shared Cassidy Biellak· 2 shared Hai P. NguyeniD· 2 shared Martin KircheriD· 2 shared Rory R. ShengiD· 2 shared Abbey BlakeiD· 1 shared Ajuni SohotaiD· 1 shared

Activity by Year

2022-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersGenomics

Nadav AhituvORCID

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5 papers

Recent·Most cited

Degraded sensory coding in a mouse model of Scn2a-related disorder and its rescue by CRISPRa gene activation

Kaeli Vandemark, Hannah R. Monday, Lucia Rodriguez, Manya Zhao, Meeseo Lee, Amit Ahituv, Anwita Satapathy, Nicholas F. Page, Kelly An, Elizabeth C. Hamada, Nadav Ahituv, Kevin J. Bender, Daniel E. Feldman

The paper shows that Scn2a loss-of-function in mice causes degraded sensory coding in the cortex, which is rescued by CRISPRa gene activation.

bioRxiv · Dec 14, 2025 · PreprintNeuroscience

Capture-C MPRA: A high-throughput method to simultaneously characterize promoter interactions and regulatory activity

Coline Arnould, Pia Keukeleire, Fumitaka Inoue, Xiekui Cui, Kelly An, Elizabeth Murray, Xuhuiqun Zhang, Radoje Drmanac, Brock A. Peters, Jay Shendure, Yin Shen, Martin Kircher, Nadav Ahituv

This paper introduces ccMPRA, a method that combines Capture-C and MPRA to study promoter interactions and regulatory activity, identifying enhancers and silencers.

bioRxiv · Jun 11, 2025 · PreprintGenomics

Massively parallel jumping assay decodes Alu retrotransposition activity

Navneet Kaur Matharu, Jingjing Zhao, Ajuni Sohota, Linbei Deng, Yan Hung, Zizheng Li, Kelly An, Jasmine Sims, Sawitree Rattanasopha, Thomas Joshua Meyer, Lucia Carbone, Martin Kircher, Nadav Ahituv

The paper develops a high-throughput assay to test retrotransposon jumping activity and identifies variants that influence transposition.

Nature Communications · May 8, 2025Peer-reviewedGenomics

Integrative single-cell characterization of hypothalamus sex-differential and obesity-associated genes and regulatory elements

Hai P. Nguyen, Candace S. Y. Chan, Dianne Laboy Cintrón, Rory R. Sheng, Lana Harshman, Mai Nobuhara, Aki Ushiki, Cassidy Biellak, Kelly An, Gracie Gordon, F. Mifsud, Abbey Blake, Eric Jinsheng Huang, Martin Hemberg, Christian Vaisse, Nadav Ahituv

The paper integrates single-cell RNA and ATAC-seq data from mouse and human hypothalamus to identify sex-specific genes and obesity-associated regulatory elements.

bioRxiv · Nov 6, 2022 · PreprintNeuroscience

ADGRG6 promotes adipogenesis and is involved in sex-specific fat distribution

Hai P. Nguyen, Aki Ushiki, Rory R. Sheng, Cassidy Biellak, Kelly An, Hélène Choquet, Thomas J. Hoffman, Ryan S. Gray, Nadav Ahituv

This study identifies ADGRG6 as a gene involved in adipogenesis and sex-specific fat distribution, showing its potential as a therapeutic target for metabolic disease.

bioRxiv · Jun 24, 2022 · PreprintGenomics