Author

Laura Perrault

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:experimental assay· 1

Frequent Co-Authors

Clifford J. WoolfiD· 2 shared Devlin FrostiD· 2 shared Kuchuan CheniD· 2 shared Riki KawaguchiiD· 2 shared Roshan Pandey· 2 shared Xuan HuangiD· 2 shared Alma L. BurlingameiD· 1 shared Bingjie ZhangiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Clifford J. WoolfORCID

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2 papers

Recent·Most cited

NEK1 modulates neurite outgrowth in motor neurons through coordinating retromer formation

Xuan Huang, Juan A. Osés-Prieto, Riki Kawaguchi, Laura Perrault, Devlin Frost, Kuchuan Chen, Feng Guo, Bingjie Zhang, Pinghan Zhao, Tammy Szu‐Yu Ho, Roshan Pandey, Daniel H. Geschwind, Alma L. Burlingame, Clifford J. Woolf

This study identifies NEK1's role in motor neuron neurite outgrowth by coordinating retromer formation through interactions with SMC3.

bioRxiv · May 6, 2024 · PreprintNeuroscience

Downregulation of the silent potassium channel Kv8.1 increases ALS motor neuron vulnerability

Xuan Huang, Seungkyu Lee, Riki Kawaguchi, Ole Wiskow, Sulagna Dia Ghosh, Devlin Frost, Laura Perrault, Roshan Pandey, Kuchuan Chen, Joseph R. Klim, Bruno Boivin, Crystal Hermawan, Kenneth J. Livak, Dan H. Geschwind, Brian J. Wainger, , Clifford J. Woolf

The paper shows that reduced Kv8.1 expression in ALS motor neurons with SOD1(A4V) and C9orf72 mutations increases vulnerability to cell death by affecting metabolism and transport pathways.

bioRxiv · May 7, 2023 · PreprintNeuroscience