Author

Lauren Gibilisco

AbbVie (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:Drosophila· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1

Frequent Co-Authors

Doris BachtrogiD· 2 shared Shivani Mahajan· 2 shared Ameya S KulkarniiD· 1 shared Astrid WachteriD· 1 shared Cindy ZadikoffiD· 1 shared Daniel J. ApiccoiD· 1 shared Hualin Simon XiiD· 1 shared Hyun Ji NohiD· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersGenomics

Doris BachtrogORCID

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Author profile →

4 papers

Recent·Most cited

Progression GWAS followed by functional characterization implicates E3 ubiquitin ligase TRIM2 as a potential genetic modifier of Parkinson's Disease progression

Ameya S Kulkarni, Daniel J. Apicco, Saleh Tamim, Lauren Gibilisco, Layan Nahlawi, Rachel McFarland Lucia, Sujana Ghosh, Samantha Lent, Yanyu Liang, Saurabh Khasnavis, LAURA B. SMITH, Joshua D. Stender, Priyanka Vijay, Cindy Zadikoff, J. Wade Davis, , Hyun Ji Noh

The paper performs a GWAS on PD progression metrics and identifies TRIM2 as a genetic modifier, showing its role in regulating neurofilament light and alpha-synuclein aggregation.

Scientific Reports · Sep 2, 2026Peer-reviewedGenetic & Genomic Medicine

ABACUS: A flexible UMI counter that leverages intronic reads for single-nucleus RNAseq analysis

Hualin Simon Xi, Lauren Gibilisco, Markus P. Kummer, Knut Biber, Astrid Wachter, Maya E. Woodbury

ABACUS improves sNuc-RNAseq analysis by incorporating intronic reads, doubling the number of identified nuclei in human brain data and enhancing cluster resolution.

bioRxiv · Nov 13, 2020 · PreprintBioinformatics

De novo assembly of a young Drosophila Y chromosome using Single-Molecule sequencing and Chromatin Conformation capture

Shivani Mahajan, Kevin H.-C. Wei, Matthew J. Nalley, Lauren Gibilisco, Doris Bachtrog

The paper assembles the Drosophila miranda Y chromosome using long reads and chromatin conformation capture, revealing its expansion through repetitive sequences.

PLoS Biology · Jul 30, 2018Peer-reviewedGenomics

The evolution of alternative splicing in Drosophila

Lauren Gibilisco, Qi Zhou, Shivani Mahajan, Doris Bachtrog

The paper examines alternative splicing patterns in Drosophila across sexes, developmental stages, and species, finding sex-specific and stage-specific splicing trends.

bioRxiv · May 21, 2016Genomics