Author

Lin Tan

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Philip L. LorenziiD· 2 shared Bo WeiiD· 1 shared Dejan ŠtepeciD· 1 shared Eiru KimiD· 1 shared Huimin ZhangiD· 1 shared Iqbal MahmudiD· 1 shared John N. WeinsteiniD· 1 shared Maximilien BurqiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Philip L. LorenziORCID

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2 papers

Recent·Most cited

Integrating Narrow-Window DIA with AI-Powered Search Enables Deep and Reliable Functional Proteomics

Yun Xiong, Dejan Štepec, Huimin Zhang, Lin Tan, Bo Wei, Maximilien Burq, John N. Weinstein, Peter Cimermančič, Philip L. Lorenzi

The paper benchmarks nDIA and related proteomics methods, showing nDIA with DIA-NN and Tesorai Search provides high coverage and reliable results in proteomic analysis.

bioRxiv · Sep 10, 2026 · PreprintSystems Biology

Therapeutic modulation of ROCK overcomes metabolic adaptation of cancer cells to OXPHOS inhibition and drives synergistic anti-tumor activity

Nicholas Blazanin, Xiaobing Liang, Iqbal Mahmud, Eiru Kim, Sara Martinez, Lin Tan, Waikin Chan, Nazanin Esmaeili Anvar, Min Jin Ha, Md Qudratullah, Rosalba Minelli, Michael D. Peoples, Philip L. Lorenzi, Traver Hart, Yonathan Lissanu

This study identifies ROCK inhibition as a strategy to overcome metabolic adaptation in cancer cells to OXPHOS inhibition, showing synergistic anti-tumor effects.

bioRxiv · Sep 16, 2024 · PreprintCancer Biology