Author

Lina Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Agathe Bernand· 1 shared Ashwin JainarayananiD· 1 shared Brienne McKenzieiD· 1 shared Claire C. StatoniD· 1 shared Emma CiniiD· 1 shared Frecia Rodriguez· 1 shared Laurence LamantiD· 1 shared Lucie DemeerssemaniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Agathe Bernand

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1 paper

Recent·Most cited

Perforin-mediated pore formation at the lytic synapse triggers the canonical pyroptotic cell death pathway

Brienne McKenzie, Marie-Pierre Puisségur, Lucie Demeersseman, Frecia Rodriguez, Emma Cini, Ashwin Jainarayanan, Marcus A. Widdess, Claire C. Staton, Lina Chen, Vincent Sibaud, Laurence Lamant, Michael Loran Dustin, Agathe Bernand, Sabina Müller, Salvatore Valitutti

This study shows perforin triggers pyroptosis in target cells by activating the NLRP3/caspase-1/gasdermin D pathway, while sustained CTL interaction leads to apoptosis.

bioRxiv · May 24, 2024 · PreprintCell Biology