Author

M. A. Davies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. d. Bruin· 1 shared A. H. Grossmann· 1 shared A. Rogers· 1 shared B. A. Davies· 1 shared B. G. Childs· 1 shared C. Chattopadhyay· 1 shared C. P. Martin· 1 shared C. P. Rich· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

A. d. Bruin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma

C. Chattopadhyay, J. Roszik, R. Bhattacharya, M. Alauddin, I. Mahmud, S. Yadugiri, M. M. Ali, F. S. Khan, V. V. Prabhu, P. Lorenzi, E. Burton, R. R. Morey, R. Lazcano, M. A. Davies, S. P. Patel, E. A. Grimm

The paper tests imipridones in a mouse model of uveal melanoma, finding they reduce tumor growth and improve survival by targeting oxidative phosphorylation.

bioRxiv · Jan 12, 2024Cancer Biology

ARF6-dependent endocytic trafficking of the Interferon-γ receptor drives adaptive immune resistance in cancer.

Y. Wee, J. Wang, E. C. Wilson, C. P. Rich, A. Rogers, Z. Tong, E. DeGroot, Y. N. V. Gopal, M. A. Davies, H. A. Ekiz, J. K. H. Tay, C. Stubben, K. M. Boucher, J. M. Oviedo, K. Fairfax, , A. H. Grossmann

This study identifies ARF6-dependent endocytic trafficking of the IFN-gamma receptor as a mechanism driving adaptive immune resistance in cancer, linking it to immune checkpoint blockade efficacy.

bioRxiv · Sep 29, 2023Cancer Biology

HD-PTP/PTPN23 hypomorphic mice display lipodystrophy

B. A. Davies, J. A. Payne, C. P. Martin, D. Schultz, B. G. Childs, C. Zhang, K. Jeganathan, I. Sturmlechner, T. A. White, A. d. Bruin, H. Chen, M. A. Davies, S. Jachim, N. K. LeBrasseur, R. C. Piper, , D. J. Katzmann

This study shows that hypomorphic HD-PTP/PTPN23 mice develop lipodystrophy and reduced adipogenesis, indicating HD-PTP's role in insulin signaling and fat accumulation.

bioRxiv · Aug 2, 2022 · PreprintCell Biology