Author

P. Michalak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Evolutionary Biology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:Drosophila· 2 Organism:human· 2 Organism:mouse· 2 Organism:Arabidopsis· 1 Approach:biophysical modeling· 1 Organism:chicken / avian· 1

Frequent Co-Authors

A. M. Brown· 2 shared J. Weger-Lucarelli· 2 shared L. Kang· 2 shared A. A. Carbonello· 1 shared A. Adam· 1 shared A. B. Korol· 1 shared A. Hardy· 1 shared A. Henrion Lacritick· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

A. M. Brown

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Author profile →

7 papers

Recent·Most cited

Can seminal fluid proteins be honest signals of sperm availability?

P. Michalak, D. Duneau, J.-B. Ferdy

The paper models how seminal fluid peptides synchronize sperm and egg release in Drosophila, showing SP exhaustion as a key signal and limiting sexual conflict over remating behavior.

bioRxiv · Apr 26, 2024 · PreprintEvolutionary Biology

Humoral and T-cell-mediated responses to a pre-clinical Zika vaccine candidate that utilizes a unique insect-specific flavivirus platform

D. L. Porier, A. Adam, L. Kang, P. Michalak, J. Tupik, M. A. Santos, C. Lee, I. C. Allen, T. Wang, A. J. Auguste

This study evaluates immune responses to an ISFV-based Zika vaccine, showing neutralizing antibodies and T-cells contribute to protection.

bioRxiv · Mar 1, 2023 · PreprintMicrobiology

The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito

F. Roesch, C. Cereghino, L. Carrau, A. Hardy, H. Ribeiro-Filho, A. Henrion Lacritick, C. Koh, J. Marano, T. A. Bates, P. Rai, C. Chuong, S. Akter, T. Vallet, H. Blanc, T. Elliot, , J. Weger-Lucarelli

This paper identifies a mutation in the E2 glycoprotein of Mayaro virus that enhances transmission in Aedes aegypti but reduces replication in human cells, suggesting a trade-off in host adaptation.

bioRxiv · Apr 5, 2022 · PreprintMicrobiology

The mating system affects the temperature sensitivity of male and female fertility

J. Baur, D. Jagusch, P. Michalak, M. Koppik, D. Berger

This study shows that mating system influences thermal sensitivity of fertility, with females showing higher sensitivity than males, and this sex difference can evolve rapidly under sexual selection.

bioRxiv · Jun 9, 2021Ecology

Co-Infection of cattle in Virginia with Theileria orientalis ikeda genotype and Anaplasma marginale

V. J. Oakes, s. m. todd, A. A. Carbonello, P. Michalak, K. K. Lahmers

This paper develops a duplex qPCR assay to detect co-infection of Theileria orientalis ikeda and Anaplasma marginale in Virginia cattle, finding co-infection occurs in 12 out of 1,359 samples.

bioRxiv · Apr 28, 2021Microbiology

A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation

L. Kang, G. He, A. K. Sharp, X. Wang, A. M. Brown, P. Michalak, J. Weger-Lucarelli

The paper identifies a selective sweep in the Spike gene of SARS-CoV-2 that enhanced human adaptation by improving binding to human ACE2 and replication in human cells.

bioRxiv · Feb 13, 2021Microbiology

Seasonal changes in recombination rate, crossover interference, and their response to desiccation stress in a natural population of Drosophila melanogaster from India

D. D. Aggarwal, S. Rybnikov, S. Sapielkin, E. Rashkovetsky, Z. Frenkel, M. Singh, P. Michalak, A. B. Korol

The paper examines seasonal changes in recombination rate and crossover interference in Drosophila melanogaster, finding genetic differences in desiccation tolerance and recombination patterns between winter and autumn populations.

bioRxiv · Jun 17, 2020Evolutionary Biology