Author

M. A. Schneider

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 7 Research Focus:cell type annotation· 5 Research Focus:differential expression· 4 Research Focus:cell-cell communication· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Approach:statistical model· 3 Approach:microscopy & imaging analysis· 2

Frequent Co-Authors

T. Muley· 5 shared H. Winter· 4 shared M. Meister· 3 shared C. Conrad· 2 shared K. Jechow· 2 shared M. Thomas· 2 shared P. Christopoulos· 2 shared R. Eils· 2 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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5 shared papersCancer Biology

T. Muley

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A single-sample workflow for joint metabolomic and proteomic analysis of clinical specimens

H. Gegner, T. Naake, K. Aljakouch, A. Dugourd, G. Kliewer, T. Mueller, D. Schilling, M. A. Schneider, N. Kunze, T. G. P. Gruenewald, R. Hell, J. Saez-Rodriguez, W. Huber, G. Poschet, J. Krijgsveld

The paper introduces a single-sample workflow, MTBE-SP3, for simultaneous proteomic and metabolomic analysis, showing it reduces technical variation and enables consistent results across biological matrices.

bioRxiv · Nov 7, 2023 · PreprintCancer Biology

Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis

A.-K. Daum, L. Schlicker, M. A. Schneider, T. Muley, U. Klingmüller, A. Schulze, M. Thomas, P. Christopoulos, H. Sültmann

This study shows cancer-associated fibroblasts enhance drug resistance in ALK-driven lung adenocarcinoma by promoting lipid biosynthesis and suppressing lipid peroxidation through AKT signaling.

bioRxiv · Aug 8, 2023 · PreprintCancer Biology

The pregnancy-associated protein glycodelin as a potential sex-specific target for resistance to immunotherapy in non-small cell lung cancer

S. Richtmann, S. Marwitz, T. Muley, H. Koistinnen, P. Christopoulos, M. Thomas, D. N. Kazdal, M. Allgaeuer, H. Winter, T. Goldmann, M. Meister, U. Klingmueller, M. A. Schneider

This paper identifies glycodelin as a sex-specific factor influencing immunotherapy resistance in NSCLC, showing it impairs survival in female patients and interacts with immune cells.

bioRxiv · Mar 2, 2023Cancer Biology

High-resolution epigenetic profiling identifies novel regulators of COPD in human lung fibroblasts

U. Schwartz, M. Llamazares Prada, S. T. Pohl, M. Richter, R. Tamas, M. Schuler, C. Keller, V. Mijosek, T. Muley, M. A. Schneider, K. Quast, J. Hey, C. P. Heussel, A. Warth, H. Winter, , R. Jurkowska

This study identifies novel epigenetic and transcriptomic regulators of COPD in human lung fibroblasts across disease stages.

bioRxiv · Mar 28, 2022 · PreprintCell Biology

Quantitative imaging reveals PI3Kδ inhibition reduces rhinovirus-induced damage of small airway epithelia in ex vivo cultured human precision cut lung slices from COPD patients

D. Dvornikov, A. Halavatyi, M. M. Khan, N. Zimmerman, A. Cross, D. Poeckel, E. Melnikov, C. M. Tischer, J. Leyrer, M. A. Schneider, T. Muley, H. Winter, E. Hessel, S. Beinke, R. Pepperkok

bioRxiv · Mar 1, 2022 · PreprintPathology

Intratumoural heterogeneity and immune modulation in lung adenocarcinoma of female smokers and never smokers

T. B. Trefzer, M. A. Schneider, K. Jechow, L. R. Chua, T. Muley, H. Winter, M. Kriegsmann, M. Meister, R. Eils, C. Conrad

The paper examines intratumoural heterogeneity and immune modulation in lung adenocarcinoma, focusing on female smokers and never smokers, identifying distinct cellular subpopulations and immune interactions.

bioRxiv · May 18, 2021Cancer Biology

Resolving Drug Effects In Patient-Derived Cancer Cells Links Organoid Responses To Genome Alterations

J. Neugebauer, F. M. Zickgraf, J. Park, S. Wagner, X. Jiang, K. Jechow, K. Kleinheinz, U. H. Toprak, M. A. Schneider, M. Meister, S. Spaich, M. Suetterlin, M. Schlesner, A. Trumpp, M. Sprick, , C. Conrad

The paper compares drug responses in ovarian cancer organoids and monolayer cultures, finding differences in drug efficacy and genomic associations.

bioRxiv · Apr 6, 2017Cancer Biology