Mucins form a nanoscale material barrier against immune cell attack
S. Park, M. J. Colville, C. R. Shurer, L.-T. Huang, J. C.-H. Kuo, J. H. Paek, M. C. Goudge, J. Su, M. P. DeLisa, J. Lammerding, W. R. Zipfel, C. Fischbach, H. L. Reesink, M. J. Paszek
This study investigates how glycocalyx thickness, influenced by mucin properties, affects NK cell-mediated cytotoxicity and suggests strategies to enhance cancer immunotherapy.
bioRxiv · Jan 28, 2022 · PreprintBiophysics