Author

M. J. Colville

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Assay:fluorescence / live-cell microscopy· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. J. Paszek· 4 shared J. C.-H. Kuo· 3 shared L.-T. Huang· 3 shared W. R. Zipfel· 3 shared J. Lammerding· 2 shared M. C. Goudge· 2 shared M. P. DeLisa· 2 shared S. Park· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersBiophysics

M. J. Paszek

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Bio-orthogonal Glycan Imaging of Culture Cells and Whole Animal C. elegans with Expansion Microscopy

J. C.-H. Kuo, M. J. Colville, M. R. Sorkin, J. L. K. Kuo, L.-T. Huang, D. N. Thornlow, G. M. Beacham, G. Hollopeter, M. P. DeLisa, C. A. Alabi, M. J. Paszek

This paper develops multifunctional reagents for nanoscale imaging of glycans using expansion microscopy, validated in C. elegans and mammalian cells.

bioRxiv · Feb 1, 2024 · PreprintBioengineering

Mucins form a nanoscale material barrier against immune cell attack

S. Park, M. J. Colville, C. R. Shurer, L.-T. Huang, J. C.-H. Kuo, J. H. Paek, M. C. Goudge, J. Su, M. P. DeLisa, J. Lammerding, W. R. Zipfel, C. Fischbach, H. L. Reesink, M. J. Paszek

This study investigates how glycocalyx thickness, influenced by mucin properties, affects NK cell-mediated cytotoxicity and suggests strategies to enhance cancer immunotherapy.

bioRxiv · Jan 28, 2022 · PreprintBiophysics

Nuclear deformation causes DNA damage by increasing replication stress

P. Shah, C. M. Hobson, S. Cheng, M. J. Colville, M. Paszek, R. Superfine, J. Lammerding

The paper shows that nuclear deformation during migration or compression causes DNA damage by increasing replication stress, primarily in S/G2 phase, independent of nuclear envelope rupture.

Current Biology · Feb 1, 2021Peer-reviewedCell Biology

Litmus-Body: a Molecularly Targeted Sensor for Cell-Surface pH Measurements

M. C. Goudge, J. C.-H. Kuo, A. E. Metzloff, L.-T. Huang, M. J. Colville, W. R. Zipfel, M. J. Paszek

The paper introduces a molecularly targeted pH sensor called Litmus-body, capable of measuring cell-surface pH with high specificity and sensitivity.

bioRxiv · Oct 10, 2019 · PreprintCell Biology

High-speed device synchronization in optical microscopy with an open-source hardware control platform

M. J. Colville, S. Park, W. R. Zipfel, M. J. Paszek

The paper develops an open-source hardware control platform for high-speed device synchronization in optical microscopy, demonstrating its application in various scanning techniques and reducing synchronization artifacts.

bioRxiv · Jan 29, 2019Biophysics