Author

L.-T. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Plant Biology· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Organism:plant (other)· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. C.-H. Kuo· 3 shared M. J. Colville· 3 shared M. J. Paszek· 3 shared B.-J. Chiang· 2 shared C.-H. Wu· 2 shared C.-Y. Huang· 2 shared K.-Y. Lin· 2 shared M. C. Goudge· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBioengineering

J. C.-H. Kuo

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Development of a tightly regulated copper-inducible transient gene expression system in Nicotiana benthamiana incorporating suicide exon and Cre recombinase

B.-J. Chiang, K.-Y. Lin, Y.-F. Chen, C.-Y. Huang, F.-J. Goh, L.-T. Huang, L.-H. Chen, C.-H. Wu

This paper develops a copper-inducible gene expression system in Nicotiana benthamiana to tightly regulate transgene expression and cell death assays.

bioRxiv · Mar 23, 2024 · PreprintPlant Biology

Bio-orthogonal Glycan Imaging of Culture Cells and Whole Animal C. elegans with Expansion Microscopy

J. C.-H. Kuo, M. J. Colville, M. R. Sorkin, J. L. K. Kuo, L.-T. Huang, D. N. Thornlow, G. M. Beacham, G. Hollopeter, M. P. DeLisa, C. A. Alabi, M. J. Paszek

This paper develops multifunctional reagents for nanoscale imaging of glycans using expansion microscopy, validated in C. elegans and mammalian cells.

bioRxiv · Feb 1, 2024 · PreprintBioengineering

Functional divergence shaped the network architecture of plant immune receptors

C.-Y. Huang, Y.-S. Huang, Y. Sugihara, H.-Y. Wang, L.-T. Huang, J. C. Lopez-Agudelo, Y.-F. Chen, K.-Y. Lin, B.-J. Chiang, A. Toghani, J. Kourelis, L. Derevnina, C.-H. Wu

The paper shows how functional divergence in NRC3 variants shapes the genetic architecture of the NLR network in solanaceous plants, leading to subfunctionalization and increased immune system complexity.

bioRxiv · Dec 12, 2023 · PreprintPlant Biology

Mucins form a nanoscale material barrier against immune cell attack

S. Park, M. J. Colville, C. R. Shurer, L.-T. Huang, J. C.-H. Kuo, J. H. Paek, M. C. Goudge, J. Su, M. P. DeLisa, J. Lammerding, W. R. Zipfel, C. Fischbach, H. L. Reesink, M. J. Paszek

This study investigates how glycocalyx thickness, influenced by mucin properties, affects NK cell-mediated cytotoxicity and suggests strategies to enhance cancer immunotherapy.

bioRxiv · Jan 28, 2022 · PreprintBiophysics

Litmus-Body: a Molecularly Targeted Sensor for Cell-Surface pH Measurements

M. C. Goudge, J. C.-H. Kuo, A. E. Metzloff, L.-T. Huang, M. J. Colville, W. R. Zipfel, M. J. Paszek

The paper introduces a molecularly targeted pH sensor called Litmus-body, capable of measuring cell-surface pH with high specificity and sensitivity.

bioRxiv · Oct 10, 2019 · PreprintCell Biology

Active Transport of Membrane Components by Self-Organization of the Min Proteins

Y.-L. Shih, L.-T. Huang, Y.-M. Tu, B.-F. Lee, Y.-C. Bau, C. Y. Hong, H.-l. Lee, Y.-P. Shih, M.-F. Hsu, J.-S. Chen, Z.-X. Lu, L. Chao

The paper shows that Min protein waves create steric pressure to direct membrane component distribution, following a physical principle similar to peristaltic pumping.

bioRxiv · Sep 14, 2018Biophysics