Author

W. R. Zipfel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:fluorescence / live-cell microscopy· 3 Assay:imaging· 3 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. J. Colville· 3 shared M. J. Paszek· 3 shared J. C.-H. Kuo· 2 shared L.-T. Huang· 2 shared M. C. Goudge· 2 shared S. Park· 2 shared A. C. Vill· 1 shared A. E. Metzloff· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiophysics

M. J. Colville

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Spatial Mapping of Mobile Genetic Elements and their Cognate Hosts in Complex Microbiomes

B. Grodner, H. Shi, O. Farchione, A. C. Vill, I. Ntekas, P. J. Diebold, W. R. Zipfel, I. L. Brito, I. De Vlaminck

The paper develops an imaging method to map mobile genetic elements and their bacterial hosts in human oral biofilms, revealing spatial clusters of AMR plasmids and prophage.

bioRxiv · Jun 9, 2023 · PreprintMicrobiology

Mucins form a nanoscale material barrier against immune cell attack

S. Park, M. J. Colville, C. R. Shurer, L.-T. Huang, J. C.-H. Kuo, J. H. Paek, M. C. Goudge, J. Su, M. P. DeLisa, J. Lammerding, W. R. Zipfel, C. Fischbach, H. L. Reesink, M. J. Paszek

This study investigates how glycocalyx thickness, influenced by mucin properties, affects NK cell-mediated cytotoxicity and suggests strategies to enhance cancer immunotherapy.

bioRxiv · Jan 28, 2022 · PreprintBiophysics

Fluorophore-labelled RNA aptamers to common protein tags as super-resolution imaging reagents.

J. Wang, A. Singh, A. Ozer, W. R. Zipfel

This paper demonstrates RNA aptamer-based labeling methods for super-resolution imaging of proteins fused to common tags, showing advantages for live cell imaging and quantifying plasma membrane protein trafficking.

bioRxiv · Feb 27, 2020 · PreprintBiophysics

Litmus-Body: a Molecularly Targeted Sensor for Cell-Surface pH Measurements

M. C. Goudge, J. C.-H. Kuo, A. E. Metzloff, L.-T. Huang, M. J. Colville, W. R. Zipfel, M. J. Paszek

The paper introduces a molecularly targeted pH sensor called Litmus-body, capable of measuring cell-surface pH with high specificity and sensitivity.

bioRxiv · Oct 10, 2019 · PreprintCell Biology

High-speed device synchronization in optical microscopy with an open-source hardware control platform

M. J. Colville, S. Park, W. R. Zipfel, M. J. Paszek

The paper develops an open-source hardware control platform for high-speed device synchronization in optical microscopy, demonstrating its application in various scanning techniques and reducing synchronization artifacts.

bioRxiv · Jan 29, 2019Biophysics