Author

M. Chalabi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

D. Ruano· 1 shared E. E. Voest· 1 shared F. Koning· 1 shared G. Bultynck· 1 shared G. Gillet· 1 shared I. Mikaelian· 1 shared J. B. Haanen· 1 shared J. v. d. Bulk· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

D. Ruano

Mutual co-authors in cluster

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2 papers

Recent·Most cited

γδ T cells are effectors of immune checkpoint blockade in mismatch repair-deficient colon cancers with antigen presentation defects

N. L. de Vries, J. v. d. Haar, V. Veninga, M. Chalabi, M. E. Ijsselsteijn, M. v. d. Ploeg, J. v. d. Bulk, D. Ruano, J. B. Haanen, T. N. Schumacher, L. F. A. Wessels, F. Koning, N. F. C. C. de Miranda, E. E. Voest

This study shows that γδ T cells, not CD8+ T cells, mediate immune checkpoint blockade efficacy in HLA class I-negative, MMR-d colon cancers.

bioRxiv · Oct 14, 2021 · PreprintCancer Biology

The Endoplasmic Reticulum pool of Bcl-xL dampens the Unfolded Protein Response through IP3R-dependent Calcium Release

L. Jabbour, T. Nguyen, R. Gadet, O. Lohez, I. Mikaelian, P. Gonzalo, T. Luyten, M. Chalabi, G. Bultynck, R. Rimokh, G. Gillet, N. Popgeorgiev

This study shows that Bcl-xL at the endoplasmic reticulum (ER) dampens the unfolded protein response (UPR) by reducing IP3R-mediated calcium release, thereby preventing ER calcium depletion and cell death.

bioRxiv · Jan 27, 2021 · PreprintCell Biology