Author

M. D. Shields

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

L. Broadbent· 2 shared U. F. Power· 2 shared A. Miller· 1 shared B. Faubert· 1 shared B. Ko· 1 shared B. Timmons· 1 shared C. Yang· 1 shared D. Shames· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

L. Broadbent

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inhibition of the TLR4 signalling pathway with TAK-242 reduces RSV infection and cytokine release in primary airway epithelial cells

L. Broadbent, G. C. Roberts, J. D. Coey, J. Barabas, M. D. Shields, U. F. Power, the Breathing Together Consortium

bioRxiv · Nov 22, 2021 · PreprintMicrobiology

Comparative therapeutic potential of ALX-0171 and palivizumab against RSV clinical isolate infection of well-differentiated primary pediatric bronchial epithelial cell cultures

L. Broadbent, H. Guo Parke, L. J. Ferguson, A. Miller, M. D. Shields, L. Detalle, U. F. Power

This study compares the therapeutic efficacy of ALX-0171 and palivizumab against RSV infection in a human bronchial epithelial cell model, showing ALX-0171 is more potent at neutralizing virus but less effective at reducing viral genomic copies.

Antimicrobial Agents and Chemotherapy · Jan 27, 2020Peer-reviewedMicrobiology

METABOLIC DIVERSITY IN HUMAN NON-SMALL CELL LUNG CANCER CELLS

P.-H. CHEN, L. Cai, C. Yang, J. Kim, B. Faubert, L. Boroughs, B. Ko, J. Sudderth, E. A. McMillan, L. Girard, M. Peyton, K. Huffman, M. D. Shields, D. Shames, H. S. Kim, , R. J. DeBerardinis

The paper quantifies metabolic features in NSCLC cell lines to explore associations between metabolism and other cell-autonomous processes.

bioRxiv · Mar 11, 2019Cancer Biology