Single-molecule analysis of the entire perfringolysin O poreformation pathway
C. Mc Guinness, J. Walsh, C. Bayly-Jones, M. Dunstone, C. Morton, M. Christie, M. W. Parker, T. Boecking
This study uses single-molecule fluorescence imaging to analyze the kinetics of PFO pore formation, revealing that membrane insertion is kinetically controlled.
bioRxiv · Oct 19, 2021Biophysics