Author

I. Brown

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

A. A. Malinowska· 1 shared A. C. Banyard· 1 shared A. dos Santos· 1 shared A. F. Lingappa· 1 shared A. Jenkinson· 1 shared A. K. Shah· 1 shared A. L. B. Pyne· 1 shared A. Macieik· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperEcology

A. A. Malinowska

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

High pathogenicity avian influenza (H5N1) in Northern Gannets: Global spread, clinical signs, and demographic consequences

J. V. Lane, J. W. Jeglinski, S. Avery-Gomm, E. Ballstaedt, A. C. Banyard, T. Barychka, I. Brown, B. Brugger, T. V. Burt, N. Careen, J. H. F. Castenschoid, S. Christensen-Dalsgaard, S. Clifford, S. M. Collins, E. Cunningham, , A. A. Malinowska

This study tracks the global spread of HPAI H5N1 in Northern Gannets, documenting high mortality rates and demographic impacts across multiple colonies.

bioRxiv · May 1, 2023Ecology

Autophagy receptor NDP52 alters DNA conformation to modulate RNA Polymerase II transcription

A. dos Santos, D. E. Rollins, Y. Hari-Gupta, H. C. Reed, M. Du, S. Y. Z. Ru, K. Pidlisna, A. Stranger, F. Lorgat, I. Brown, K. Howland, J. Arron, L. Wang, P. J. Ellis, T. L. Chew, , C. P. Toseland

This study identifies NDP52's role in modulating RNA Polymerase II transcription by altering DNA conformation through direct dsDNA binding and interactions with chromatin regulators.

bioRxiv · Feb 1, 2022 · PreprintBiophysics

A Pan-respiratory Antiviral Chemotype Targeting a Host Multiprotein Complex

M. Michon, A. Mueller-Schiffmann, A. F. Lingappa, S. F. Yu, L. Du, F. Deiter, S. Mallesh, J. Crabtree, U. F. Lingappa, A. Macieik, L. Mueller, P. N. Ostermann, M. Andree, O. Adams, H. Schaal, , K

The paper identifies a novel antiviral chemotype effective against multiple respiratory viruses by targeting a host multi-protein complex involved in viral lifecycle and innate immunity.

bioRxiv · Jan 17, 2021Biochemistry

Serum glycoprotein biomarker validation for esophageal adenocarcinoma and application to Barrett’s surveillance

A. K. Shah, G. Hartel, I. Brown, C. Winterford, R. Na, K.-A. Le Cao, B. A. Spicer, M. Dunstone, W. A. Phillips, R. V. Lord, A. P. Barbour, D. I. Watson, V. Joshi, D. C. Whiteman, M. M. Hill

The paper validates serum glycoprotein biomarkers for esophageal adenocarcinoma and develops a panel for Barrett’s surveillance.

bioRxiv · Mar 13, 2018Biochemistry