Author

G. Hartel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. M. Hill· 2 shared A. H. Porter· 1 shared A. K. Shah· 1 shared A. M. Kane· 1 shared A. P. Barbour· 1 shared A. P. Sobinoff· 1 shared A. SheelaNair· 1 shared A. Song· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

M. M. Hill

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Imetelstat-Mediated Alterations in Fatty Acid Metabolism To Induce Ferroptosis As Therapeutic Strategy for Acute Myeloid Leukemia

C. Bruedigam, A. H. Porter, A. Song, G. Vroeg in de Wei, T. Stoll, J. Straube, L. Cooper, G. Cheng, V. F. S. Kahl, A. P. Sobinoff, V. Y. Ling, B. M. C. Jebaraj, Y. Janardhanan, R. Haldar, L. J. Bray, , S. W. Lane

This study identifies ferroptosis as a mechanism by which imetelstat induces therapeutic effects in AML, showing that targeting fatty acid metabolism enhances its efficacy.

bioRxiv · Apr 25, 2023Cancer Biology

Aspirin synergizes with regorafenib to reduce growth of colorectal cancer

C. Su, L. J. Fennell, C. E. Bond, A. M. Kane, G. Kerr, T. Jarde, D. Micati, R. M. Engel, W. H. Chan, S. Hlavca, S. Archer, P. J. McMurrick, H. Hammerlindl, F. Lim, B. Salik, , V. L. Whitehall

This study shows that aspirin and regorafenib together reduce colorectal cancer growth in preclinical models by inhibiting the PI3K-Akt-mTOR pathway and activating AMPK.

bioRxiv · Feb 11, 2022 · PreprintCancer Biology

Age dependent changes in circulating Tfh cells influence the development of functional antibodies to malaria in children.

J.-A. Chan, J. Loughland, L. de la Parte, S. Okano, I. Ssewanyana, M. Nalubega, F. Nankya, K. Musinguzi, J. Rek, E. Arinaitwe, P. Tipping, P. Bourke, D. Andrew, N. Dooley, A. SheelaNair, , M. J. Boyle

The paper examines age-related changes in Tfh cells and their impact on antibody development against malaria in children, finding age-dependent shifts in Tfh cell subsets and antibody responses.

bioRxiv · Dec 12, 2021Immunology

Serum glycoprotein biomarker validation for esophageal adenocarcinoma and application to Barrett’s surveillance

A. K. Shah, G. Hartel, I. Brown, C. Winterford, R. Na, K.-A. Le Cao, B. A. Spicer, M. Dunstone, W. A. Phillips, R. V. Lord, A. P. Barbour, D. I. Watson, V. Joshi, D. C. Whiteman, M. M. Hill

The paper validates serum glycoprotein biomarkers for esophageal adenocarcinoma and develops a panel for Barrett’s surveillance.

bioRxiv · Mar 13, 2018Biochemistry