Author

M. G. Roncarolo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

R. Bacchetta· 2 shared A. Bertaina· 1 shared A. J. Gentles· 1 shared A. P. Boss· 1 shared A. Ramachandran· 1 shared A.-M. Cepika· 1 shared B. A. Luca· 1 shared B. C. Thomas· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

R. Bacchetta

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

AML/T cell interactomics uncover correlates of patient outcomes and the key role of ICAM1 in T cell killing of AML

E. C. Sayitoglu, B. A. Luca, A. P. Boss, B. C. Thomas, R. A. Freeborn, M. J. Uyeda, P. P. Chen, Y. Nakauchi, C. Waichler, N. J. Lacayo, R. Bacchetta, R. Majeti, A. J. Gentles, A.-M. Cepika, M. G. Roncarolo

The paper identifies ICAM1 as a key factor in T cell killing of AML by analyzing transcriptional programs in AML and T cell interactions.

bioRxiv · Sep 21, 2023Immunology

Loss of FOXP3 function causes expansion of two pools of autoreactive T cells in patients with IPEX syndrome.

S. Borna, E. Lee, U. Lakshmanan, M. Mavers, M. Narula, A. Ramachandran, J. Baker, J. Schulze, S. Olek, L. Marois, Y. Gernez, M. Bhatia, A. Bertaina, M. G. Roncarolo, E. Meffre, R. Bacchetta

FOXP3 mutations in humans lead to expansion of autoreactive T cells from both effector and regulatory T cells that gain effector function.

bioRxiv · Jul 10, 2022Immunology

Gene Correction for SCID-X1 in Long-Term Hematopoietic Stem Cells

M. Pavel-Dinu, V. Wiebking, B. T. Dejene, W. Srifa, S. Mantri, C. Nicolas, C. Lee, G. Bao, E. J. Kildebeck, N. Punjya, C. Sindhu, M. A. Inlay, N. Saxena, S. S. DeRavin, H. Malech, , M. Porteus

This study corrects SCID-X1 in hematopoietic stem cells using CRISPR/Cas9, achieving high integration frequencies and low off-target effects, supporting clinical development.

bioRxiv · Aug 22, 2018Bioengineering