Author

E. Meffre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Bertaina· 1 shared A. Han· 1 shared A. Iwasaki· 1 shared A. M. Ring· 1 shared A. Marson· 1 shared A. Ramachandran· 1 shared B. Israelow· 1 shared B. R. Shy· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. Bertaina

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dynamic phosphatase-recruitment controls B-cell selection and oncogenic signaling

J. Lee, M. E. Robinson, R. Sun, K. Kume, N. Ma, K. N. Cosgun, L. N. Chan, E. Leveille, H. Geng, V. S. Vykunta, B. R. Shy, A. Marson, S. G. Katz, J. Chen, E. Paietta, , M. Mueschen

This study identifies CD25 as a scaffold for phosphatases that regulate B-cell signaling and oncogenic processes, with opposing effects on B-cell malignancies and autoimmunity.

bioRxiv · Mar 13, 2023 · PreprintImmunology

Loss of FOXP3 function causes expansion of two pools of autoreactive T cells in patients with IPEX syndrome.

S. Borna, E. Lee, U. Lakshmanan, M. Mavers, M. Narula, A. Ramachandran, J. Baker, J. Schulze, S. Olek, L. Marois, Y. Gernez, M. Bhatia, A. Bertaina, M. G. Roncarolo, E. Meffre, R. Bacchetta

FOXP3 mutations in humans lead to expansion of autoreactive T cells from both effector and regulatory T cells that gain effector function.

bioRxiv · Jul 10, 2022Immunology

Inflammasome activation in infected macrophages drives COVID-19 pathology

E. Sefik, R. Qu, C. Junqueira, E. Kaffe, H. Mirza, J. Zhao, J. R. Brewer, A. Han, H. R. Steach, B. Israelow, H. N. Blackburn, S. Velazquez, Y. G. Chen, S. Halene, A. Iwasaki, , R. A. Flavell

This study shows SARS-CoV-2 infection of human macrophages drives COVID-19 pathology through inflammasome activation, leading to inflammation and pyroptosis, but also enabling viral release.

bioRxiv · Sep 27, 2021Immunology

REAP: A platform to identify autoantibodies that target the human exoproteome

E. Y. Wang, Y. Dai, C. E. Rosen, M. M. Schmitt, M. X. Dong, E. M. N. Ferre, F. Liu, Y. Yang, J. A. Gonzalez-Hernandez, E. Meffre, M. Hinchcliffe, F. Koumpouras, M. S. Lionakis, A. M. Ring

REAP identifies autoantibodies targeting the human exoproteome by screening patient samples against a yeast-displayed extracellular protein library, revealing known and novel reactivities in autoimmune diseases.

bioRxiv · Feb 11, 2021Immunology