Author

M. Hachisu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 5 Assay:proteomics· 2

Frequent Co-Authors

C. Nishiyama· 5 shared K. Nagata· 5 shared N. Ito· 5 shared T. Yashiro· 5 shared M. Ando· 4 shared D. Ando· 2 shared G. Ichihara· 2 shared M. Yamamoto· 2 shared

Activity by Year

2022-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersImmunology

C. Nishiyama

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5 papers

Recent·Most cited

The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling

M. Ando, K. Nagata, R. Takeshita, N. Ito, S. Noguchi, N. Minamikawa, N. Kodama, A. Yamamoto, T. Yashiro, M. Hachisu, G. Ichihara, S. Kishino, M. Yamamoto, J. Ogawa, C. Nishiyama

This study identifies 10-oxo-cis-6,trans-11-octadecadienoic acid as an anti-inflammatory metabolite that suppresses colitis in mice via NRF2 pathway activation and GPCR signaling.

bioRxiv · Feb 22, 2023Immunology

Immunostimulatory effects of Bacillus coagulans SANK70258

Y. Ikeda, N. Ito, N. Yamashita, N. Minamikawa, K. Nagata, T. Yashiro, M. Aida, R. Yamada, M. Hachisu, C. Nishiyama

This study evaluates the immunomodulating effects of Bacillus coagulans SANK70258, showing it induces high IFN-γ and IgA production compared to other lactic acid bacteria.

bioRxiv · Feb 21, 2023Immunology

Kaempferol suppresses the activation of mast cells by modulating the expression of FcϵRI and SHIP1

K. Nagata, S. Araumi, D. Ando, M. Ando, N. Ito, Y. Ikeda, M. Takahashi, S. Noguchi, T. Yashiro, M. Hachisu, C. Nishiyama

This study shows kaempferol suppresses mast cell activation by reducing FcεRI surface expression and increasing SHIP1 levels, independent of transcription and translation.

bioRxiv · Feb 20, 2023Immunology

Butyrate, valerate, and niacin ameliorate anaphylaxis by suppressing IgE-dependent mast cell activation: Roles of GPR109A, PGE2, and epigenetic regulation

K. Nagata, D. Ando, T. Ashikari, K. Ito, R. Miura, I. Fujigaki, M. Ando, N. Ito, H. Kawazoe, Y. Iizuka, M. Inoue, T. Yashiro, M. Hachisu, K. Kasakura, C. Nishiyama

This study shows that butyrate and valerate reduce IgE-mediated mast cell activation by enhancing PGE2 release and GPR109A signaling, while niacin also alleviates anaphylaxis through similar mechanisms.

bioRxiv · Feb 19, 2023Immunology

A rose flavor compound activating the NRF2 pathway in dendritic cells ameliorates contact hypersensitivity in mice

N. Kodama, H. Okada, M. Hachisu, M. Ando, N. Ito, K. Nagata, Y. Yasuda, I. Hiroki, T. Yashiro, G. Ichihara, M. Yamamoto, C. Nishiyama

This study shows that β-damascone, a rose compound, activates the NRF2 pathway in dendritic cells to reduce immune responses and alleviate contact hypersensitivity in mice.

bioRxiv · Feb 8, 2022Immunology