Author

C. Nishiyama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 8 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 9 Organism:mouse· 8 Research Focus:host-pathogen & immune response· 7 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

K. Nagata· 8 shared N. Ito· 8 shared T. Yashiro· 7 shared M. Ando· 5 shared M. Hachisu· 5 shared N. Minamikawa· 4 shared M. Takahashi· 3 shared D. Ando· 2 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

8 shared papersImmunology

K. Nagata

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Roles of C/EBPα, GATA2, TGF-β-signaling, and epigenetic regulation in the expression of basophil-specific protease genes

R. Tojima, K. Nagata, N. Ito, T. Arai, K. Ishii, T. Ito, K. Kasakura, C. Nishiyama

The paper investigates the transcriptional regulation of basophil-specific protease genes Mcpt8 and Mcpt11, identifying C/EBPα, GATA2, TGF-β signaling, and epigenetic factors as key regulators.

bioRxiv · Feb 24, 2024Immunology

Kaempferol exerts anti-inflammatory effects by accelerating Treg development via AhR-mediated and PU.1/IRF4-dependent transactivation of the Aldh1a2/RALDH2 gene in dendritic cells

M. Takahashi, K. Nagata, Y. Watanuki, M. Yamaguchi, N. Minamikawa, M. Katagiri, W. Zhao, N. Ito, T. Yashiro, C. Nishiyama

This study identifies kaempferol as a flavonoid that enhances Treg development via AhR-mediated and PU.1/IRF4-dependent activation of Aldh1a2/RALDH2 in dendritic cells, reducing inflammation in a food allergy model.

bioRxiv · Feb 21, 2024Immunology

NR4A3 deficiency ameliorates contact hypersensitivity and exacerbates psoriasis by regulating gene expression in dendritic cells

M. Katagiri, N. Ito, K. Nagata, S. Nakano, N. Minamikawa, N. Yamashita, M. Takahashi, M. Kurihara, M. Nagaoka, M. Ando, T. Ito, T. Yashiro, A. Yoshimura, C. Nishiyama

This study shows NR4A3 deficiency reduces contact hypersensitivity but worsens psoriasis by altering dendritic cell gene expression.

bioRxiv · Feb 20, 2024 · PreprintImmunology

The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling

M. Ando, K. Nagata, R. Takeshita, N. Ito, S. Noguchi, N. Minamikawa, N. Kodama, A. Yamamoto, T. Yashiro, M. Hachisu, G. Ichihara, S. Kishino, M. Yamamoto, J. Ogawa, C. Nishiyama

This study identifies 10-oxo-cis-6,trans-11-octadecadienoic acid as an anti-inflammatory metabolite that suppresses colitis in mice via NRF2 pathway activation and GPCR signaling.

bioRxiv · Feb 22, 2023Immunology

Immunostimulatory effects of Bacillus coagulans SANK70258

Y. Ikeda, N. Ito, N. Yamashita, N. Minamikawa, K. Nagata, T. Yashiro, M. Aida, R. Yamada, M. Hachisu, C. Nishiyama

This study evaluates the immunomodulating effects of Bacillus coagulans SANK70258, showing it induces high IFN-γ and IgA production compared to other lactic acid bacteria.

bioRxiv · Feb 21, 2023Immunology

Kaempferol suppresses the activation of mast cells by modulating the expression of FcϵRI and SHIP1

K. Nagata, S. Araumi, D. Ando, M. Ando, N. Ito, Y. Ikeda, M. Takahashi, S. Noguchi, T. Yashiro, M. Hachisu, C. Nishiyama

This study shows kaempferol suppresses mast cell activation by reducing FcεRI surface expression and increasing SHIP1 levels, independent of transcription and translation.

bioRxiv · Feb 20, 2023Immunology

Butyrate, valerate, and niacin ameliorate anaphylaxis by suppressing IgE-dependent mast cell activation: Roles of GPR109A, PGE2, and epigenetic regulation

K. Nagata, D. Ando, T. Ashikari, K. Ito, R. Miura, I. Fujigaki, M. Ando, N. Ito, H. Kawazoe, Y. Iizuka, M. Inoue, T. Yashiro, M. Hachisu, K. Kasakura, C. Nishiyama

This study shows that butyrate and valerate reduce IgE-mediated mast cell activation by enhancing PGE2 release and GPR109A signaling, while niacin also alleviates anaphylaxis through similar mechanisms.

bioRxiv · Feb 19, 2023Immunology

A rose flavor compound activating the NRF2 pathway in dendritic cells ameliorates contact hypersensitivity in mice

N. Kodama, H. Okada, M. Hachisu, M. Ando, N. Ito, K. Nagata, Y. Yasuda, I. Hiroki, T. Yashiro, G. Ichihara, M. Yamamoto, C. Nishiyama

This study shows that β-damascone, a rose compound, activates the NRF2 pathway in dendritic cells to reduce immune responses and alleviate contact hypersensitivity in mice.

bioRxiv · Feb 8, 2022Immunology

Interleukin-11 is a Marker for Both Cancer- and Inflammation-Associated Fibroblasts that Contribute to Colorectal Cancer Progression

T. Nishina, Y. Deguchi, W. Takeda, M. Ohtsuka, D. Ohshima, S. Yamazaki, M. Kawauchi, E. Nakamura, C. Nishiyama, Y. Kojima, S. Adachi-Akemi, M. Hasegawa, M. Nakayama, M. Ohshima, H. Yagita, , H. Nakano

This study identifies IL-11 as a marker for fibroblasts involved in colorectal cancer progression, showing their role in tumor development through a feed-forward loop.

bioRxiv · Jan 25, 2020 · PreprintCancer Biology