Author

M. K. Ali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. Spiekerkoetter· 4 shared M. R. Nicolls· 4 shared K. Schimmel· 3 shared L. Zhao· 3 shared C. J. Rhodes· 2 shared J. C. Wu· 2 shared Y. Liu· 2 shared A. Cao· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersCell Biology

E. Spiekerkoetter

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Rat microbial biogeography and age-dependent lactic acid bacteria in healthy lungs

L. Zhao, C. Cunningham, A. M. Andruska, K. Schimmel, M. K. Ali, D. Kim, S. Gu, J. Chang, E. Spiekerkoetter, M. R. Nicolls

This study defines the microbial biogeography of healthy Fischer 344 rats across their lifespan and identifies age-dependent changes in lactic acid bacteria in the lungs.

bioRxiv · May 19, 2023Microbiology

Decreasing ELK3 expression improves Bone Morphogenetic Protein Receptor 2 signaling and pulmonary vascular cell function in PAH

M. K. Ali, L. Zhao, V. A. d. J. Perez, M. R. Nicolls, E. Spiekerkoetter

The paper shows that reducing ELK3 expression enhances BMPR2 signaling and improves pulmonary vascular cell function in pulmonary arterial hypertension.

bioRxiv · Jan 14, 2023 · PreprintCell Biology

PTPN1 deficiency modulates BMPR2 signaling and induces endothelial dysfunction in Pulmonary Arterial Hypertension

M. K. Ali, X. Tian, L. Zhao, K. Schimmel, C. J. Rhodes, M. Wilkins, M. R. Nicolls, E. Spiekerkoetter

This study identifies PTPN1 as a regulator of BMPR2 signaling in PAH, showing its downregulation in PAH patients and link to endothelial dysfunction.

bioRxiv · Nov 27, 2022Cell Biology

Identifying transcriptomic downstream targets of genes commonly mutated in Hereditary Hemorrhagic Telangiectasia

M. K. Ali, Y. Liu, K. Schimmel, N. H. Juul, C. A. Stockman, J. C. Wu, E. Spiekerkoetter

This study identifies common downstream transcriptomic targets of HHT-causing genes and discovers Brivanib as a potential therapeutic for HHT.

bioRxiv · Nov 25, 2022 · PreprintCell Biology

Long non-coding RNA RGMB-AS1 as a novel modulator of Bone Morphogenetic Protein Receptor 2 signaling in pulmonary arterial hypertension

M. K. Ali, Y. Liu, J. C. Wu, V. d. J. Perez, C. J. Rhodes, A. Cao, M. R. Wilkins, M. R. Nicolls, E. F. Spiekerkoetter

This study identifies RGMB-AS1 as an upregulated lncRNA in PAH that modulates BMPR2 signaling and improves vascular cell function when inhibited.

bioRxiv · Aug 27, 2022 · PreprintCell Biology