Y.-L. Wu

StomaVision: stomatal trait analysis through deep learning

StomaVision automates stomatal trait analysis from micrographs, revealing physiological responses to heat stress across plant species.

Particle fusion of Single Molecule Localization Microscopy data reveals dimer structure of Nup96 in Nuclear Pore Complex

The paper uses particle fusion of single molecule localization microscopy data to determine the dimer structure of Nup96 in the Nuclear Pore Complex, showing 32 copies per pore.

Nanoscale structural organization and stoichiometry of the budding yeast kinetochore

This study uses single-molecule localization microscopy to analyze the structure and stoichiometry of the budding yeast kinetochore, proposing a quantitative model based on nanoscale measurements.

DNA-free CRISPR-Cas9 gene editing of tetraploid tomatoes using protoplast regeneration

DNA-free CRISPR-Cas9 editing in wild tomatoes generates stable, inheritable diploid and tetraploid regenerants without chromosomal changes or off-target effects.

Superresolution microscopy reveals partial preassembly and subsequent bending of the clathrin coat during endocytosis

The paper uses superresolution microscopy to show clathrin coats partially assemble on flat membranes before bending, and introduces a model to explain this process.

Maximum-likelihood model fitting for quantitative analysis of SMLM data

LocMoFit is an open-source framework that fits models to SMLM data using maximum likelihood estimation to extract biological insights from single-molecule localization coordinates.

Long-Term Outcomes of Pediatric Graves Disease Patients Treated with Anti-Thyroid Drugs: Experience from a Taiwan Medical Center

This study examines long-term outcomes of pediatric Graves disease patients treated with anti-thyroid drugs, finding that younger age, no family history of thyroid disease, and lower TRAb levels are associated with remission.

Nuclear pores as versatile reference standards for quantitative superresolution microscopy

The paper uses genome-edited cell lines with labeled nuclear pore complexes to serve as reference standards for quantitative superresolution microscopy.

Depth-dependent PSF calibration and aberration correction for 3D single-molecule localization

This paper develops a method to correct depth-induced aberrations in 3D single-molecule localization microscopy by using an imperfect PSF model and post-processing error correction.