F. Almeida

Extracellular vesicles produced during fungal infection in humans are immunologically active

This study identifies and characterizes extracellular vesicles from human fungal infections, showing their role in modulating host immune responses through metabolite-mediated polarization of macrophages.

Deacetylation by sirtuins is important for Aspergillus fumigatus pathogenesis and virulence

This study shows that sirtuins in Aspergillus fumigatus are important for virulence and pathogenesis, with AfSirE deletion reducing virulence and altering protein acetylation and gene expression.

Aspergillus fumigatus acetate utilisation impacts virulence traits and pathogenicity

This paper investigates how acetate utilization by Aspergillus fumigatus affects virulence traits and pathogenicity, showing its role in secondary metabolite secretion, cell wall composition, and in vivo virulence.

Fungal extracellular vesicles are involved in intraspecies intracellular communication

This study shows fungal extracellular vesicles mediate intraspecies communication by regulating gene expression and phenotypic changes in Candida albicans, Aspergillus fumigatus, and Paracoccidioides brasiliensis.

Aspergillus fumigatus G-protein coupled receptors GprM and GprJ are important for the regulation of the cell wall integrity pathway, secondary metabolite production, and virulence

This paper investigates the role of GprM and GprJ GPCRs in A. fumigatus, showing they regulate cell wall integrity, secondary metabolite production, and virulence.

Functional characterization of clinical isolates of the opportunistic fungal pathogen Aspergillus nidulans

This study characterizes two clinical isolates of A. nidulans, showing differences in growth, metabolism, stress response, and virulence compared to a reference strain.

What does mitogenomics tell us about the evolutionary history of the Drosophila buzzatii cluster (repleta group)

This study assembles six mitogenomes from five Drosophila buzzatii cluster species to investigate their phylogenetic relationships and divergence times, finding support for monophyly and two main clades.

Galectin-3 inhibits Paracoccidioides brasiliensis growth and impacts paracoccidioidomycosis through multiple mechanisms

This study shows Galectin-3 inhibits Paracoccidioides brasiliensis growth and affects extracellular vesicle stability, suggesting a direct antimicrobial role in paracoccidioidomycosis.

Postnatal development of skeletal muscle in IUGR pigs: morphofunctional phenotype and molecular mechanisms

This study examines the postnatal skeletal muscle development in IUGR pigs, finding altered fiber composition and gene expression patterns compared to normal weight pigs.