Author

M. L. Sanderson-Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

D. Ly· 2 shared J. D. McArthur· 2 shared A. J. Cork· 1 shared B. L. Schulz· 1 shared D. M. De Oliveira· 1 shared G. Dougan· 1 shared H. K. N. Vyas· 1 shared H. Vyas· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

D. Ly

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Author profile →

3 papers

Recent·Most cited

An Optimised GAS-pharyngeal cell biofilm model

H. K. N. Vyas, J. D. McArthur, M. L. Sanderson-Smith

This paper optimizes a host cell-GAS biofilm model to support long-term biofilm formation of various GAS M-types, closely resembling in vivo biofilms.

bioRxiv · Nov 25, 2020Microbiology

Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes

S. Brouwer, T. C. Barnett, D. Ly, K. J. Kasper, D. M. De Oliveira, T. Rivera-Hernandez, A. J. Cork, L. McIntyre, M. G. Jespersen, J. Richter, B. L. Schulz, G. Dougan, V. Nizet, K.-Y. Yuen, Y. You, , M. J. Walker

This study identifies prophage-encoded exotoxins in Streptococcus pyogenes that enhance colonization fitness and pathogenesis in scarlet fever.

bioRxiv · May 17, 2020Microbiology

Streptococcus pyogenes M1T1 variants activate caspase-1 and induce an inflammatory neutrophil phenotype

J. G. Williams, D. Ly, N. J. Geraghty, J. D. McArthur, H. Vyas, J. Gorman, J. A. Tsatsaronis, R. Sluyter, M. L. Sanderson-Smith

This study shows that M1T1 GAS variants induce caspase-1 activation and an inflammatory neutrophil phenotype, promoting inflammation but not bacterial clearance.

bioRxiv · Mar 2, 2020 · PreprintMicrobiology