Author

M. Landis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Klestzick· 1 shared A. Oza· 1 shared A. Thompson· 1 shared B. Liebeskind· 1 shared C. Hachicho· 1 shared C. L. Vizcarra· 1 shared C. M. Rojas· 1 shared D. Nambiar· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBiochemistry

A. Klestzick

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Author profile →

4 papers

Recent·Most cited

Deep learning and likelihood approaches for viral phylogeography converge on the same answers whether the inference model is right or wrong

A. Thompson, B. Liebeskind, E. J. Scully, M. Landis

This paper compares deep learning and likelihood methods for viral phylogeography, finding they produce similar results and robustness to model errors, with deep learning being significantly faster.

bioRxiv · Feb 8, 2023Evolutionary Biology

ACSS2 Regulates HIF-2α Degradation through the E3-Ubiquitin Ligase MUL1 in Clear Cell Renal Cell Carcinoma

Z. A. Bacigalupa, W. A. Brown, E. S. Krystofiak, M. M. Wolf, R. A. Hongo, M. Landis, E. K. Amason, K. E. Beckermann, J. C. Rathmell, W. K. Rathmell

This study shows ACSS2 promotes HIF-2 stability by preventing its interaction with MUL1, and inhibiting ACSS2 reduces HIF-2 levels and suppresses ccRCC growth.

bioRxiv · Apr 21, 2022 · PreprintCancer Biology

Alterations to the broad-spectrum formin inhibitor SMIFH2 improve potency

M. Orman, M. Landis, A. Oza, D. Nambiar, J. Gjeci, K. Song, V. Huang, A. Klestzick, C. Hachicho, S. Q. Liu, J. M. Kamm, F. Bartolini, J. J. Vadakkan, C. M. Rojas, C. L. Vizcarra

The paper tests SMIFH2 and its derivatives against human formins, finding that modifications enhance potency but do not allow distinction between conserved FH2 domains.

bioRxiv · Mar 10, 2022 · PreprintBiochemistry

Punctuated evolution shaped modern vertebrate diversity

M. Landis, J. G. Schraiber

This study uses a novel maximum likelihood framework to test if punctuated evolution explains modern vertebrate diversity better than gradual models.

bioRxiv · Jun 18, 2017Evolutionary Biology