Author

Z. A. Bacigalupa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

C. D. Katsetos· 1 shared C. M. Ferrer· 1 shared E. K. Amason· 1 shared E. S. Krystofiak· 1 shared J. C. Rathmell· 1 shared J. G. Jackson· 1 shared J. Ju· 1 shared K. E. Beckermann· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

C. D. Katsetos

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ACSS2 Regulates HIF-2α Degradation through the E3-Ubiquitin Ligase MUL1 in Clear Cell Renal Cell Carcinoma

Z. A. Bacigalupa, W. A. Brown, E. S. Krystofiak, M. M. Wolf, R. A. Hongo, M. Landis, E. K. Amason, K. E. Beckermann, J. C. Rathmell, W. K. Rathmell

This study shows ACSS2 promotes HIF-2 stability by preventing its interaction with MUL1, and inhibiting ACSS2 reduces HIF-2 levels and suppresses ccRCC growth.

bioRxiv · Apr 21, 2022 · PreprintCancer Biology

O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation

L. Ciraku, Z. A. Bacigalupa, J. Ju, R. A. Moeller, R. H. Lee, M. D. Smith, C. M. Ferrer, S. Trefely, M. T. Doan, W. A. Gocal, L. D'Agostino, W. Shi, J. G. Jackson, C. D. Katsetos, N. W. Snyder, M. J. Reginato

This study identifies OGT's role in regulating GBM acetate metabolism through CDK5-dependent ACSS2 phosphorylation, showing that targeting this pathway inhibits tumor growth.

bioRxiv · May 10, 2021Cancer Biology