Author

M. M. Olcina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Giaccia· 2 shared D. K. Nambiar· 2 shared M. Stucki· 2 shared Q.-T. Le· 2 shared R. K. Kim· 2 shared S. Melemenidis· 2 shared T. M. Woodruff· 2 shared A. C. Koong· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. J. Giaccia

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Innate immune receptor C5aR1 regulates cancer cell fate and can be targeted to improve radiotherapy in tumours with immunosuppressive microenvironments

C. Beach, D. MacLean, D. Majorova, S. Melemenidis, D. K. Nambiar, R. K. Kim, G. N. Valbuena, S. Guglietta, C. Krieg, M. D. Damavandi, T. Suwa, A. Easton, E. Domingo, E. J. Moon, D. Jiang, , M. M. Olcina

This study identifies C5aR1 as a targetable receptor on cancer cells that enhances radiotherapy efficacy in immunosuppressive tumours by promoting apoptosis without affecting normal tissues.

bioRxiv · Jan 10, 2023 · PreprintCancer Biology

Targeting C5aR1 Increases the Therapeutic Window of Radiotherapy

M. M. Olcina, S. Melemenidis, D. K. Nambiar, R. K. Kim, K. M. Casey, R. von Eyben, T. M. Woodruff, E. G. Graves, Q.-T. Le, M. Stucki, A. J. Giaccia

This study shows that targeting C5aR1 with PMX205 improves tumor radiation response and reduces normal tissue toxicity in mice.

bioRxiv · Oct 27, 2020 · PreprintCancer Biology