M. McKenzie

WNT Signalling Promotes NF-κB Activation and Drug Resistance in KRAS-Mutant Colorectal Cancer

This study shows that WNT signaling enhances NF-κB activation and drug resistance in KRAS-mutant colorectal cancer, suggesting a therapeutic strategy targeting WNT and MEK pathways.

Amyloid beta 42 alters cardiac metabolism and impairs cardiac function in obesity

This study shows that amyloid beta 42 from adipose tissue impairs cardiac function in obesity by affecting mitochondrial metabolism, and that neutralizing A{beta} can prevent obesity-induced cardiac dysfunction.

Fishing for mammals: landscape-level monitoring of terrestrial and semi-aquatic communities using eDNA from lotic ecosystems

This study evaluates eDNA metabarcoding for detecting terrestrial and semi-aquatic mammals in lotic ecosystems, finding it effective and comparable to traditional methods.