Sequential roles for red blood cell binding proteins enable phased commitment to invasion for malaria parasites
M. N. Hart, F. Mohring, S. M. Donvito, J. A. Thomas, N. Muller-Sienerth, G. J. Wright, E. Knuepfer, H. R. Saibil, R. W. Moon
This study identifies the sequential roles of DBP and NBPXa in P. knowlesi merozoite invasion of human RBCs, revealing a phased commitment mechanism that can be targeted with antibodies.
bioRxiv · Aug 9, 2022Cell Biology