D. Richter

Glial Reactivity and Cognitive Decline Follow Chronic Heterochromatin Loss in Neurons

The paper shows chronic heterochromatin loss in neurons leads to ERV de-repression, inflammation, and cognitive decline in mice.

Transportome remodeling of a symbiotic microalga inside a planktonic host

This study identifies sugar transporter remodeling in a symbiotic microalga, revealing how metabolic exchange is reprogrammed during photosymbiosis with a planktonic host.

Endothelial cannabinoid CB1 receptor deficiency reduces arterial inflammation and lipid uptake in response to atheroprone shear stress

This paper shows that blocking endothelial CB1 receptors reduces arterial inflammation and lipid uptake under atheroprone shear stress, suggesting potential therapeutic benefits for atherosclerosis.

Cerebrospinal fluid outflow through skull channels instructs cranial hematopoiesis

The paper shows cerebrospinal fluid exits through skull channels into bone marrow, and bacteria use this route during meningitis to initiate cranial hematopoiesis.

Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals

The paper examines how TRNP1's regulatory and coding sequences co-evolve with brain size and cortical folding across mammals, finding significant correlations with brain size and increased TRNP1 activity.

Imaging mechanical properties of sub-micron ECM in live zebrafish using Brillouin microscopy

This study uses Brillouin microscopy to measure the thickness and mechanical properties of the ECM in live zebrafish, finding it to be ~400nm thick.

Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells

This study shows that eIF2B filament formation in starved yeast cells regulates translation by acidification-induced assembly, independent of Gcn2 kinase, promoting stress survival and recovery.

The ancestral animal genetic toolkit revealed by diverse choanoflagellate transcriptomes

This study reconstructs the ancestral animal gene repertoire by analyzing 19 additional choanoflagellate transcriptomes, revealing gene families previously thought to be animal-specific actually evolved earlier.