Collective invasion of the basement membrane in breast cancer driven by forces from cell volume expansion and local contractility
J. Chang, A. Saraswathibhatla, Z. Song, S. Varma, C. Sanchez, S. Srivastava, K. Liu, M. C. Bassik, M. P. Marinkovich, L. Hodgson, V. Shenoy, R. B. West, O. Chaudhuri
This study shows breast cancer cells invade the basement membrane using both proteases and mechanical forces from cell volume expansion and local contractility.
bioRxiv · Jul 28, 2022 · PreprintCancer Biology