Author

A. Saraswathibhatla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. C. Bassik· 2 shared O. Chaudhuri· 2 shared A. Esclamado· 1 shared B. Ha· 1 shared C. Franck· 1 shared C. J. Allan· 1 shared C. Sanchez· 1 shared D. Indana· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

M. C. Bassik

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2 papers

Recent·Most cited

Monocytes use protrusive forces to generate migration paths in viscoelastic collagen-based extracellular matrices

K. Adebowale, C. J. Allan, B. Ha, A. Saraswathibhatla, J. Zhu, D. Indana, M. Popescu, S. Demirdjian, H. A. Martinez, A. Esclamado, J. Yang, M. C. Bassik, C. Franck, P. Bollyky, O. Chaudhuri

This study shows that monocytes migrate through viscoelastic collagen matrices by generating protrusive forces via actin polymerization, with increased matrix stiffness and viscoelasticity enhancing their 3D migration.

bioRxiv · Jun 9, 2023Cell Biology

Collective invasion of the basement membrane in breast cancer driven by forces from cell volume expansion and local contractility

J. Chang, A. Saraswathibhatla, Z. Song, S. Varma, C. Sanchez, S. Srivastava, K. Liu, M. C. Bassik, M. P. Marinkovich, L. Hodgson, V. Shenoy, R. B. West, O. Chaudhuri

This study shows breast cancer cells invade the basement membrane using both proteases and mechanical forces from cell volume expansion and local contractility.

bioRxiv · Jul 28, 2022 · PreprintCancer Biology