Author

M. R. Baker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 2 Biophysics· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:cryo-EM· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:protein structure prediction· 2 Organism:zebrafish· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

G. Fan· 3 shared I. I. Serysheva· 3 shared D. I. Yule· 2 shared L. E. Terry· 2 shared M. L. Baker· 2 shared R. Y. Wong· 2 shared S. J. Ludtke· 2 shared V. Arige· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersBiophysics

G. Fan

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Author profile →

5 papers

Recent·Most cited

Structural dynamics underlying gating and regulation in IP3R channel

G. Fan, M. R. Baker, L. E. Terry, V. Arige, M. Chen, A. Seryshev, M. L. Baker, S. J. Ludtke, D. I. Yule, I. I. Serysheva

The paper determines 3D structures of IP3R1 in two ligand-bound states using cryo-EM and identifies dynamic properties of key domains involved in ligand binding and channel gating.

bioRxiv · May 27, 2022Biophysics

Functional Determination of Calcium Binding Sites Required for the Activation of Inositol 1,4,5-trisphosphate receptors.

V. Arige, L. E. Terry, L. E. Wagner, M. R. Baker, G. Fan, I. I. Serysheva, D. I. Yule

This study identifies acidic residues in IP3Rs critical for Ca2+ binding and activation, showing their role in modulating channel activity and Ca2+ sensitivity.

bioRxiv · Mar 7, 2022Physiology

Npas4a expression in the teleost forebrain is associated with stress coping style differences in fear learning

M. R. Baker, R. Y. Wong

The paper examines how npas4a gene expression in zebrafish forebrain regions correlates with stress coping styles in fear learning.

bioRxiv · Nov 24, 2020Animal Behavior & Cognition

Contextual fear learning and memory differ between stress coping styles in zebrafish

M. R. Baker, R. Y. Wong

This study compares contextual fear learning and memory in zebrafish with proactive and reactive stress coping styles, finding differences in learning rate and memory retention.

bioRxiv · Jan 30, 2019Animal Behavior & Cognition

Cryo-EM Reveals Ligand Induced Allostery Underlying InsP3R Channel Gating

G. Fan, M. R. Baker, Z. Wang, A. B. Serysheva, S. J. Ludtke, M. L. Baker, I. I. Serysheva

The paper presents cryo-EM structures of InsP3R1 in activated and apo-states, revealing ligand-induced conformational changes that underlie channel gating.

bioRxiv · Jul 23, 2018Biophysics