Author

L. E. Terry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. I. Yule· 4 shared V. Arige· 3 shared G. Fan· 2 shared I. I. Serysheva· 2 shared L. E. Wagner· 2 shared M. R. Baker· 2 shared A. Seryshev· 1 shared G.-Y. Son· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersPhysiology

D. I. Yule

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural dynamics underlying gating and regulation in IP3R channel

G. Fan, M. R. Baker, L. E. Terry, V. Arige, M. Chen, A. Seryshev, M. L. Baker, S. J. Ludtke, D. I. Yule, I. I. Serysheva

The paper determines 3D structures of IP3R1 in two ligand-bound states using cryo-EM and identifies dynamic properties of key domains involved in ligand binding and channel gating.

bioRxiv · May 27, 2022Biophysics

Functional Determination of Calcium Binding Sites Required for the Activation of Inositol 1,4,5-trisphosphate receptors.

V. Arige, L. E. Terry, L. E. Wagner, M. R. Baker, G. Fan, I. I. Serysheva, D. I. Yule

This study identifies acidic residues in IP3Rs critical for Ca2+ binding and activation, showing their role in modulating channel activity and Ca2+ sensitivity.

bioRxiv · Mar 7, 2022Physiology

Functional Communication between IP3R and STIM2 at sub-threshold stimuli is a critical checkpoint for initiation of SOCE

M. Ahmad, H. L. Ong, H. Saadi, G.-Y. Son, Z. Shokatian, L. E. Terry, M. Trebak, D. I. Yule, I. Ambudkar

This study identifies IP3R-mediated local [Ca2+]ER decreases as the driver of immobile STIM2 clusters at ER-PM junctions, marking a checkpoint for SOCE initiation under sub-threshold stimuli.

bioRxiv · Sep 24, 2021 · PreprintPhysiology

CREB regulates the expression of Type 1 Inositol 1,4,5-trisphosphate receptors

V. Arige, L. E. Terry, T. R. Knebel, L. E. Wagner, D. I. Yule

This study shows that CREB regulates IP3R1 expression and localization, affecting Ca2+ release and puffs.

bioRxiv · May 5, 2021Physiology