Osmotic Stress Influences Microtubule Drug Response Via WNK1 Kinase Signaling
A. Monfort-Vengut, N. Sanz-Gomez, S. Ballesteros-Sanchez, B. Ortigosa, A. Cambon, M. Ramos, A. Montes-San Lorenzo, J. M. Rosa-Rosa, J. Martinez-Lopez, R. Sanchez-Prieto, R. Sotillo, G. de Carcer
The paper identifies WNK1 kinase as a modulator of microtubule drug response under osmotic stress, showing altered drug sensitivity due to changes in microtubule stability.
bioRxiv · Jul 8, 2024Cancer Biology