Author

M. S. Almeida

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. S. Pinheiro· 2 shared M. J. Amaral· 2 shared T. S. Araujo· 2 shared A. A. Vasconcelos· 1 shared A. H. Futerman· 1 shared A. L. Marques· 1 shared A. Peden· 1 shared A. T. Da Poian· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiophysics

A. S. Pinheiro

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Author profile →

4 papers

Recent·Most cited

Structure insights, thermodynamic profiles, dsDNA melting activity, and liquid-liquid phase separation of the SARS-CoV-2 nucleocapsid N-terminal domain binding to DNA

I. P. Caruso, V. S. Almeida, M. J. Amaral, G. C. Andrade, G. R. Araujo, T. S. Araujo, J. M. Azevedo, G. M. Barbosa, L. Bartkevihi, P. R. Bezerra, K. M. d. S. Cabral, I. O. Lourenco, C. L. F. Malizia-Motta, A. L. Marques, N. C. Mebus-Antunes, , F. C. L. Almeida

This study examines the structural and thermodynamic properties of SARS-CoV-2 N-terminal domain binding to DNA, revealing specific interactions and phase separation behavior.

bioRxiv · Jul 21, 2021 · PreprintBiophysics

Cholesteryl Hemiazelate Induces Lysosome Dysfunction and Exocytosis in Macrophages

N. Domingues, R. D. A. Calado, P. Brito, R. Matthiesen, J. Ramalho, M. I. L. Soares, T. Pereira, L. Oliveira, J. Vicente, L. H. Wong, S. M. Cho, I. Simoes, J. Sampaio, C. Klose, M. A. Surma, , O. V. Vieira

This study identifies cholesteryl hemiazelate as a cause of lysosome dysfunction and exocytosis in macrophages, contributing to atherosclerosis.

bioRxiv · Jan 5, 2021 · PreprintCell Biology

Biophysical characterization of two commercially available preparations of the drug containing Escherichia coli L-Asparaginase 2

T. S. Araujo, S. M. Scapin, W. Andrade, M. Fasciotti, M. T. de Magalhaes, M. S. Almeida, L. M. T. d. R. Lima

This study compares two commercial E. coli L-Asparaginase 2 preparations using biophysical methods, revealing differences in conformational dynamics and proteolysis resistance linked to L-aspartic acid presence.

bioRxiv · Nov 11, 2020Biophysics

Liquid-liquid phase separation and aggregation of the prion protein globular domain modulated by a high-affinity DNA aptamer

C. O. Matos, Y. M. Passos, M. J. Amaral, B. Macedo, M. Tempone, O. C. L. Bezerra, M. O. Moraes, M. S. Almeida, G. Weber, S. Missailidis, J. L. Silva, A. S. Pinheiro, Y. Cordeiro

This study identifies DNA aptamers that modulate liquid-liquid phase separation of prion protein, revealing structural effects on aggregation and potential implications for TSEs.

bioRxiv · Jun 3, 2019Biophysics