Author

M. S. Piepenbrink

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

A. Deshpande· 3 shared J. J. Kobie· 3 shared L. Martinez-Sobrido· 3 shared M. Basu· 3 shared M. R. Walter· 3 shared A. Loos· 2 shared C. Ye· 2 shared J. Woo· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

A. Deshpande

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structure and Epitope of a Neutralizing Monoclonal Antibody that Targets the Stem Helix of β Coronaviruses

A. Deshpande, N. Schormann, M. S. Piepenbrink, L. Martinez-Sobrido, J. Kobie, M. R. Walter

This paper determines the crystal structure of a broadly neutralizing antibody targeting the stem helix of coronaviruses and elucidates its mechanism of neutralization.

bioRxiv · Sep 14, 2022Immunology

Potent universal-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody

M. S. Piepenbrink, J.-G. Park, A. Deshpande, A. Loos, C. Ye, M. Basu, S. Sarkar, D. Chauvin, J. Woo, P. Lovalenti, N. B. Erdmann, P. A. Goepfert, V. L. Truong, R. A. Bowen, M. R. Walter, , J. J. Kobie

This study identifies a potent universal coronavirus neutralizing monoclonal antibody, 1249A8, effective against multiple variants and demonstrating therapeutic activity through intranasal administration.

bioRxiv · Mar 5, 2022 · PreprintImmunology

Mixed Origins: HIV gp120-specific memory develops from pre-existing memory and naive B cells following vaccination in humans

M. Basu, M. S. Piepenbrink, C. Fucile, C. A. Bunce, L.-X. Man, J. Liesveld, A. F. Rosenberg, M. C. Keefer, J. J. Kobie

This study shows that HIV gp120-specific memory B cells arise from both naive and pre-existing cross-reactive memory B cells following vaccination.

bioRxiv · Sep 1, 2021Immunology

Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters

M. S. Piepenbrink, J.-G. Park, F. Oladunni, A. Deshpande, M. Basu, S. Sarkar, A. Loos, J. Woo, P. Lovalenti, D. Sloan, C. Ye, K. Chiem, N. B. Erdmann, P. A. Goepfert, V. L. Truong, , J. J. Kobie

This study evaluates an inhaled monoclonal antibody against SARS-CoV-2 in hamsters, showing reduced viral burden and lung pathology with low-dose inhalation.

bioRxiv · Oct 14, 2020Immunology