Author

Man K.S. Lee

Baker Heart and Diabetes Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew James MurphyiD· 2 shared Aascha BrowniD· 1 shared Annas Al‐Sharea· 1 shared Arpeeta SharmaiD· 1 shared Christopher Graeme SobeyiD· 1 shared Daniel G. DonneriD· 1 shared Grant Raymond DrummondiD· 1 shared Hannah X. ChuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Andrew James MurphyORCID

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2 papers

Recent·Most cited

Inhibition of Gasdermin D by Disulfiram Attenuates Cardiac Inflammation and Fibrosis following Ischaemia Reperfusion Injury

Judy S.Y. Choi, Mehnaz Pervin, Helen Kiriazis, Parvin Yavari, Aascha Brown, Man K.S. Lee, Andrew James Murphy, Daniel G. Donner, James Edward Vince, Arpeeta Sharma, Judy B. de Haan

This paper shows that Disulfiram reduces cardiac inflammation and fibrosis after heart attack by inhibiting the GSDMD pathway.

bioRxiv · Mar 12, 2026 · PreprintImmunology

S100A8/A9 Inhibition Reduces Splenic Myelopoiesis and Improves Outcomes After Stroke

Hyun Ah Kim, Annas Al‐Sharea, Hannah X. Chu, Sung‐Chun Tang, Samoda Rupasinghe, Shenpeng R. Zhang, Prabhakara R. Nagareddy, Grant Raymond Drummond, Thiruma Valavan Arumugam, Andrew James Murphy, Christopher Graeme Sobey, Man K.S. Lee

This study shows that S100A8/A9 inhibition reduces splenic myelopoiesis and improves stroke outcomes by decreasing neutrophilia and infarct size.

Frontiers in Immunology · Feb 17, 2026Peer-reviewedNeuroscience