Maozhen Qin

A high-performance genetically encoded sensor for cellular imaging of PKC activity in vivo

The paper introduces a genetically encoded fluorescence sensor for PKC activity, demonstrating its use in vivo and identifying PKC activity in specific neurons during locomotion.

Cerebellar climbing fibers convey perceptual choice during decision-making

This study shows that cerebellar climbing fibers encode perceptual choices during decision-making in mice, with their activity reshaped by learning and critical for discrimination.

Prevalent co-release of glutamate and GABA throughout the mouse brain

The paper demonstrates that glutamate and GABA are co-released by neurons in multiple brain regions, as evidenced by biphasic miniature postsynaptic currents observed in striatal neurons and other areas.

Highly sensitive genetically-encoded sensors for population and subcellular imaging of cAMP in vivo

The paper develops improved genetically-encoded cAMP sensors, cAMPFIREs, for high-sensitivity in vivo imaging of cAMP dynamics in neurons and Drosophila.

Distinct in vivo dynamics of excitatory synapses onto cortical pyramidal neurons and inhibitory interneurons

The paper uses in vivo imaging to compare synaptic dynamics between excitatory synapses on pyramidal neurons and inhibitory interneurons, finding that PV+ synapses are more stable and less heterogeneous.