Author

Maram Bader

Genentech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Joanna WysockaiD· 2 shared Peter D. ClaesiD· 2 shared Tomek SwigutiD· 2 shared Alexander N. PopoviD· 1 shared Amy J. HeidersbachiD· 1 shared Andrew H. NgiD· 1 shared Angela N. PogsoniD· 1 shared Azalia Sandles· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersDevelopmental Biology

Joanna WysockaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chemically-inducible CRISPR/Cas9 circuits for ultra-high dynamic range gene perturbation

Rajini Srinivasan, Tao Sun, Azalia Sandles, Diana H. Wu, Liang Wang, Hetal Patel, Ryan Pabalate, Maram Bader, Amy J. Heidersbach, Clark Ho, Shiqi Xie, Andrew H. Ng, Benjamin Haley

This paper develops inducible CRISPR/Cas9 systems with improved dynamic range and reduced off-target effects for precise gene perturbation.

Nature Communications · Dec 12, 2025Peer-reviewedMolecular Biology

A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis

Jaaved Mohammed, Neha Arora, Harold S. Matthews, Karissa L. Hansen, Maram Bader, Susan Walsh, John R. Shaffer, Seth Michael Weinberg, Tomek Swigut, Peter D. Claes, Licia Selleri, Joanna Wysocka

The paper identifies a SNP that regulates facial shape and disease risk by affecting PKDCC expression during chondrogenesis, showing its impact on both normal variation and clefting.

eLife · Feb 19, 2024Peer-reviewedDevelopmental Biology

DNA-guided transcription factor cooperativity shapes face and limb mesenchyme

Seungsoo Kim, Ekaterina Yu. Morgunova, Sahin Naqvi, Seppe Goovaerts, Maram Bader, Mervenaz Koska, Alexander N. Popov, Christy Luong, Angela N. Pogson, Tomek Swigut, Peter D. Claes, Jussi Taipale, Joanna Wysocka

The paper shows how DNA motifs guide transcription factor cooperativity in embryonic face and limb mesenchyme, shaping cell identity and morphology.

Cell · Jan 22, 2024Peer-reviewedGenomics