Author

Margarida Sancho

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Aida Di Gregorio· 1 shared Alistair P. GreeniD· 1 shared Ana LimaiD· 1 shared Antonio ScialdoneiD· 1 shared Bárbara PernauteiD· 1 shared David CarlingiD· 1 shared Di HuiD· 1 shared Elmir MahammadoviD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Aida Di Gregorio

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1 paper

Recent·Most cited

Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development

Ana Lima, Gabriele Lubatti, Jörg Patrick Burgstaller, Di Hu, Alistair P. Green, Aida Di Gregorio, Tamzin Zawadzki, Bárbara Pernaute, Elmir Mahammadov, Salvador Pérez-Montero, Marian H. Dore, Juan Miguel Sánchez, Sarah Bowling, Margarida Sancho, Thomas Kolbe, , Tristan A. Rodríguez

The paper identifies mitochondrial defects in eliminated cells during early mouse development and shows that cell competition removes cells with mitochondrial DNA mutations and sequence changes.

Nature Metabolism · Jul 12, 2021Peer-reviewedDevelopmental Biology